FCGR3A - Fc gamma receptor IIIa Gene

Also Known as CD16; FCG3; CD16A; FCGR3; IGFR3; IMD20; FCR-10; FCRIII; CD16-II; FCGRIII; FCRIIIA; FcGRIIIA

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 2214

About FCGR3A

Cytogenetic location: 1q23.3 Genomic coordinates (GRCh38): 1:161,541,759-161,550,737 (from NCBI)

This gene has 14 transcripts (splice variants), 215 orthologues, 17 paralogues and is associated with 2 phenotypes. Biased expression in spleen (RPKM 154.1), lung (RPKM 70.6) and 10 other tissues.

Summary

This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as Other responses, including antibody dependent cellular mediated cytotoxicity and antibody dependent enhancement of virus infections. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene are associated with immunodeficiency 20, and have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2020]

FCGR3A Products (8)

mRNA	Protein	Name
NM_000569.8	NP_000560.7	low affinity immunoglobulin gamma Fc region receptor III-A isoform c precursor
NM_001127592.2	NP_001121064.2	low affinity immunoglobulin gamma Fc region receptor III-A isoform b
NM_001127593.1	NP_001121065.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform c precursor
NM_001127595.2	NP_001121067.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform c precursor
NM_001127596.2	NP_001121068.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform d precursor
NM_001329120.2	NP_001316049.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform c precursor
NM_001329122.1	NP_001316051.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform e
NM_001386450.1	NP_001373379.1	low affinity immunoglobulin gamma Fc region receptor III-A isoform d precursor

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	References	Source
enables immune receptor activity	IDA IDA: Inferred from direct assay	10318937	GOA
enables low-affinity IgG receptor activity	IDA IDA: Inferred from direct assay	11711607	GOA
enables protein binding	IPI IPI: Inferred from physical interaction	2532305	GOA

Biological Process GO Annotation	Evidence	References	Source
involved in Fc-gamma receptor signaling pathway	IDA IDA: Inferred from direct assay	8478617	GOA
involved in antibody-dependent cellular cytotoxicity	IDA IDA: Inferred from direct assay	11711607	GOA
involved in calcium-mediated signaling	IDA IDA: Inferred from direct assay	23024279	GOA
involved in macrophage activation	IDA IDA: Inferred from direct assay	10728755	GOA
involved in natural killer cell activation	IDA IDA: Inferred from direct assay	9916693	GOA
involved in natural killer cell activation	IMP IMP: Inferred from mutant phenotype	23006327	GOA
involved in natural killer cell degranulation	IDA IDA: Inferred from direct assay	25786175	GOA
involved in natural killer cell mediated cytotoxicity	IDA IDA: Inferred from direct assay	10318937	GOA
involved in phosphatidylinositol 3-kinase/protein kinase B signal transduction	IDA IDA: Inferred from direct assay	23024279	GOA
involved in positive regulation of natural killer cell proliferation	IDA IDA: Inferred from direct assay	9916693	GOA
involved in positive regulation of tumor necrosis factor production	IDA IDA: Inferred from direct assay	10728755	GOA

Cellular Component GO Annotation	Evidence	References	Source
part of Fc-gamma receptor III complex	IDA IDA: Inferred from direct assay	1825220	GOA
located in external side of plasma membrane	IDA IDA: Inferred from direct assay	10706735	GOA
located in extracellular space	IDA IDA: Inferred from direct assay	24337742	GOA
located in plasma membrane	IDA IDA: Inferred from direct assay	1825220	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FCGR3A Protein Structure

Ig_2

0
100
200
254 a.a.

Protein Preferred Names	Protein Names
low affinity immunoglobulin gamma Fc region receptor III-A	CD16a antigen

FCGR3A Protein-protein interaction Information

Type	Protein Name	Protein ID	Interactor	Interactor Species	Interactor ID	Detection Method	References
Intra	FCGR3A	P08637	KIR2DL4	Homo sapiens	Q99706	Anti Bait CoIP	34158475
Intra	FCGR3A	P08637	RNF40	Homo sapiens	O75150	Anti Tag CoIP	33961781

Cross: Cross-species interaction Intra: Intraspecies interaction

Recombinant FCGR3A Proteins

Cat. No.	Product Name	Accession	Purity
HY-P70705	Fc gamma RIIIA/CD16a Protein, Human (HEK293, His)	P08637 (G17-Q208)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P72885	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-Avi)	P08637/AAH17865.1 (G17-Q208, F176V)	≥ 90%, as determined by reducing SDS-PAGE.
HY-P75207	Fc gamma RIIIA/CD16a Protein, Human (CHO, His)	P08637 (G17-Q208)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P75209	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His)	P08637 (G17-Q208, F176V)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P75210	Fc gamma RIIIA/CD16a Protein, Human (F176V, CHO, His)	P08637 (G17-Q208, F176V)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P77553	Fc gamma RIIIA/CD16a Protein, Human (Biotinylated, F176V, HEK293, His-Avi)	P08637 (G17-Q208, F176V)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78099	Fc gamma RIIIA/CD16a Protein, Human (Biotinylated, HEK293, His-Avi)	P08637 (G17-Q208)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78422	Fc gamma RIIIA/CD16a Protein, Human (HEK293, His-Avi)	P08637 (G17-Q208)	≥ 95%, as determined by Bis-Tris PAGE.
HY-P78676	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, SUMO-His)	P08637 (G17-Q208, F176V)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78677	Fc gamma RIIIA/CD16a Protein, Human (F176V, HEK293, His-HSA)	P08637 (G17-Q208, F176V)	≥ 95%, as determined by reducing SDS-PAGE.
HY-P78678	Fc gamma RIIIA/CD16a Protein, Human (F176, S197P, HEK293, His)	P08637 (G17-Q208, F176, S197P)	≥ 90%, as determined by reducing SDS-PAGE.

FCGR3A Antibodies

Cat. No.	Product Name	Application	Reactivity
HY-P811546	CD16 Antibody (YA10095)	WB	Human, Mouse, Rat
HY-P81202	CD16 Antibody	WB, ELISA, IHC-P, IHC-F, FC, ICC/IF	Human, Mouse, Rat
HY-P84968	CD16 Antibody (YA4660)	WB, IHC-P, ICC/IF, IF-Tissue, mIHC	Human

Related Diseases

Diseases	Alias
Immunodeficiency 20	Autosomal Recessive Primary Immunodeficiency With Defective Spontaneous Natural Killer Cell Cytotoxicity IMD20 Autosomal Recessive Primary Immunodeficiency With Defective Spontaneous Nk Cell Cytotoxicity Cd16 Deficiency Immunodeficiency, Type 20
Herpes Zoster	Shingles Zoster Herpes Zona Herpes Zoster Disease Zona Zoster Herpes Zoster Of Skin And Mucous Membranes Zoster Nos Zoster With Nervous System Involvement
Heparin-Induced Thrombocytopenia	Hit Hat Heparin-Associated Thrombocytopenia Heparin-Induced Thrombocytopenia Type 2
Cryptococcosis	Cryptococcus Neoformans Infection Torulosis Busse-Buschke'S Disease Cryptococcal Infection European Cryptococcosis Torula Infection By Cryptococcus Neoformans Cryptococcosis Infection European Blastomycosis European Blastomycotic Infection European Blastomycoses Infection Torula Histolytica Infection
Neutropenia	Leukopenia
Poliomyelitis	Polio Infantile Paralysis
Lupus Erythematosus	Lupus Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus, Systemic Subacute Cutaneous Lupus Le - [Lupus Erythematosus]
Systemic Lupus Erythematosus	Lupus Nephritis SLE Disseminated Lupus Erythematosus Systemic Lupus Erythematosus, Susceptibility To Lupus Erythematosus, Systemic Lupus Nephritis, Susceptibility To Libman-Sacks Disease Systemic Lupus Erythematosus Susceptibility To Sle - Lupus Erythematosus, Systemic Le Syndrome Lupus Lupus Erythematosus Systemic Lupus Erythematosus, Systemic, Susceptibility To Lupus Vulgaris Lupus Erythematosus, Discoid Lupus Erythematosus Systemic Lupus Erythematosus Nos Sle - [Systemic Lupus Erythematosus]
Autoimmune Disease	Autoimmune Diseases Autoimmune Hypersensitivity Disease Hypersensitivity Reaction Type Ii Disease Type Ii Hypersensitivity Reaction Disease
Thrombocytopenia	Low Platelet Count Low Platelets Decreased Platelets Platelet Dysfunction Nos
Folliculitis
Acquired Immunodeficiency Syndrome	Acquired Immune Deficiency Syndrome AIDS Acquired Immune Deficiency Acquired Immunodeficiency Acquired Immunodeficiency Due To Protein Loss
Takayasu Arteritis	Aortic Arch Syndrome Pulseless Disease Takayasu'S Arteritis Idiopathic Aortitis Young Female Arteritis Aortic Arch Arteritis Aortic Arches Defect Aortic Arch Defects Takayasu Disease Aortic Arch Syndromes Takayasu'S Disease Ta Obliterative Aortitis Aortic Arch Giant-Cell Arteritis Subclavian-Carotid Obstruction Syndrome Idiopathic Medial Aortopathy And Arteriopathy Takayasu Syndrome Obliterative Brachiocephalic Arteritis Syndrome Raeder-Harbitz Syndrome Chronic Subclavian-Carotid Obstruction Syndrome Giant-Cell Aortitis Takayasu Aortitis Nonspecific Aortoarteritis Sclerosing Aortitis And Arteritis Martorell 2 Syndrome Young Female Aortic Arch Arteritis Syndrome
Follicular Lymphoma	Lymphoma, Follicular Lymphoma Follicular Brill-Symmers' Disease Large Cell Follicular Non-Hodgkin Lymphoma Diffuse Follicle Centre Lymphoma Diffuse Follicular Lymphoma Nos Follicular Nodular Non-Hodgkin Lymphoma, Unspecified Follicular Large Cell Cleaved Or Noncleaved Lymphoma Large Cell Follicular Noncleaved Lymphoma Follicular Lymphoma With Or Without Diffuse Areas Histiocytic Follicular Lymphoma Histiocytic Nodular Lymphoma Histiocytic Nodular Malignant Lymphoma Large Cell Follicular Lymphoma Large Cell Noncleaved Follicular Lymphoma Large Cell Noncleaved Follicular Malignant Lymphoma Nodular Reticulum Cell Sarcoma Noncleaved Follicular Lymphoma
Kawasaki Disease	Mucocutaneous Lymph Node Syndrome Acute Febrile Mucocutaneous Lymph Node Syndrome Kawasaki Syndrome Kd Infantile Polyarteritis Kawasaki Disease, Susceptibility To Acute Febrile Mcls Kawasaki'S Disease Mlns KWD
Aggressive Nk-Cell Leukemia	Aggressive Nk-Cell Leukaemia Large Granular Lymphocyte Leukemia, Nk-Cell Type Natural Killer Cell Leukaemia Natural Killer Cell Leukemia Aggressive Nk Cell Leukemia Ankl Aggressive Natural Killer Cell Leukemia Ankcl Aggressive Nk-Cell Lymphoma Nk-Cell Lgl Leukemia Nk-Cell Large Granular Lymphocyte Leukemia Abnormality Of The Ankles Aggressive Natural Killer-Cell Leukemia Leukemia, Large Granular Lymphocytic Leukemia, Natural Killer Cell Large Granular Lymphocytic
Chronic Nk-Cell Lymphocytosis	Nk-Cell Large Granular Lymphocyte Lymphocytosis Chronic Lymphoproliferative Disorder Of Nk-Cells
Rheumatoid Arthritis	RA Arthritis, Rheumatoid Rheumatoid Arthritis, Susceptibility To Arthritis Or Polyarthritis, Rheumatic Atrophic Arthritis Rheumatism Arthritis Rheumatoid Polyarthritis
Spastic Paraplegia 32, Autosomal Recessive	SPG32 Autosomal Recessive Spastic Paraplegia Type 32 Hereditary Spastic Paraplegia 32 Autosomal Recessive Spastic Paraplegia 32 Spastic Paraplegia 32 Spastic Paraplegia-32
Aggressive Periodontitis	Juvenile Periodontitis Periodontitis, Juvenile Prepubertal Periodontitis
Nk Cell Deficiency
Malaria	Malaria, Susceptibility To Malaria, Resistance To Malaria, Cerebral Cerebral Malaria Malaria, Severe, Susceptibility To Malaria, Severe, Resistance To Malaria, Cerebral, Susceptibility To Induced Malaria Malaria, Vivax, Protection Against Malaria, Severe Malaria, Cerebral, Reduced Risk Of Malaria, Protection Against Resistance To Malaria Due To G6pd Deficiency Malaria Due To G6pd Deficiency Malarial Encephalitis CM Malaria Cerebral Susceptibility To Malaria Acute Pernicious Fever Aestivo-Autumnal Fever Aestivo Autumnal Malaria Chagres Fever Continued Malaria Fever Estivo-Autumnal Fever Estivo-Autumnal Malaria Estivo-Autumnal Malarial Fever Falciparum Fever Malignant Tertian Fever Malignant Tertian Malaria Pernicious Intermittent Fever Pernicious Malaria Quotidian Malaria Subtertian Fever Subtertian Malaria Fever Subtertian Malignant Tertian Malaria Tropical Malaria Algid Malaria Bilious Haemoglobinuric Fever Black Water Fever Blackwater Fever Malarial Blackwater Fever Severe Malarial Falciparum West African Fever Malarial Haematinuria Haemoglobinuric Fever Haemoglobinuric Malaria Severe Plasmodium Falciparum Malaria Malarial Haemoglobinuria Malarial Haematuria Falciparum Malaria [Malignant Tertian] Malaria Tropica Malarial Shock Chagres Virus Disease Malignant Malaria Mtm - [Malignant Tertian Malaria] Tm -[Malignant Tertian Malaria] Panama Fever St - [Subtertian Malaria] Malarial Quotidian Benign Tertian Malaria Tertian Ague Vivax Fever Plasmodium Vivax Malaria Nos Btm - [Benign Tertian Malaria] Bt - [Benign Tertian Malaria] Vivax Malaria Benign Tertian Vivax Malaria Tertian Malaria Quartan Malaria Quartan Ague Quartan Fever Plasmodium Malariae Malaria Nos Quartan Malarial Malaria By Plasmodium Malariae Malariae Malaria Ovale Tertian Malaria Plasmodium Ovale Fever Malaria Fever By Plasmodium Ovale Ovale Malaria Malaria By Plasmodium Ovale Malarial Ovale Marsh Fever Remittent Congestive Fever Coastal Fever Remittent Gastric Fever Miasmatic Fever Congestive Remittent Fever Intermittent Fever Jungle Fever Paludism Cameroon Fever Ague Corsican Fever Intermittent Bilious Fever Disease Due To Plasmodiidae Malarial Fever Plasmodiosis Remittent Fever Roman Fever Malaria Fever Nos Malaria Nos Paludal Fever Clinically Diagnosed Malaria Clinically Diagnosed Malaria Without Parasitological Confirmation Congestive Fever Malarial Cachexia Marsh Cachexia Paludal Cachexia Recurrent Malaria Remittent Malaria
Lymphoma, Non-Hodgkin, Familial	Non-Hodgkin Lymphoma Lymphoma, Non-Hodgkin NHL Lymphoma, Non-Hodgkin, Somatic Lymphoma, Follicular, Somatic Familial Non-Hodgkin Lymphoma Lymphoma Non-Hodgkins Follicular Lymphoma, Somatic Lymphosarcoma Non-Hodgkins Lymphoma
Beta-Thalassemia	Beta Thalassemia Cooley'S Anemia Mediterranean Anemia Beta Thalassemia Intermedia Erythroblastic Anemia Thalassemia, Hispanic Gamma-Delta-Beta Thalassemia Major Thalassemia Minor Beta-Plus-Thalassemia Thalassemia, Beta Beta Thalassemia Major Beta Thalassemia Minor Thalassemias, Beta- Microcytemia, Beta Type Thalassemia, Beta Type B-THAL Mediterranean Anaemia Beta Thalassaemia Syndrome Mediterranean Disease Beta Thalassaemia Disease
Human Immunodeficiency Virus Infectious Disease	Hiv Infections
T-Cell Large Granular Lymphocyte Leukemia	Large Granular Lymphocytic Leukemia Proliferation Of Large Granular Lymphocytes T-Lgl T-Cell Lgl Leukemia Large Granular Lymphocytic Leukaemia T-Cell Large Granular Lymphocyte Leukaemia Large Cell Granular Lymphogenous Leukemia T-Lgl Leukemia Leukemia Lymphocytic Large Granular Leukemia, Large Granular Lymphocytic
Felty Syndrome	Felty'S Syndrome Rheumatoid Arthritis With Splenoadenomegaly And Leukopenia Familial Felty'S Syndrome Rheumatoid Arthritis, Splenomegaly And Neutropenia Splenomegaly-Neutropenia-Rheumatoid Arthritis Syndrome Feltys Syndrome
Bacterial Infectious Disease	Bacterial Infections Bacterial Infection Nos Disease Caused By Bacteria Bacterial Disease Or Disorder
Temporal Arteritis	Polymyalgia Rheumatica Giant Cell Arteritis Cranial Arteritis Horton Disease Gca Horton'S Disease Rhizomelic Pseudopolyarthritis Arteritis Cranialis Arteritis Temporalis Horton'S Arteritis Horton'S Giant Cell Arteritis Horton'S Temporal Arteritis Horton'S Syndrome Gca - [Giant Cell Arteritis] Senile Arthritis Polymyalgia Arteritica Pmr - [Polymyalgia Rheumatica] Forestier-Certonciny Syndrome Rheumatic Polymyalgia Polymyalgia
Chickenpox	Varicella Varicella Nos
Severe Covid-19
Psoriasis
Dermatitis, Atopic	Atopic Dermatitis Atopic Eczema Dermatitis, Atopic, Susceptibility To, 1 Atod Eczema, Atopic Dermatitis, Atopic 1 Allergic Dermatitis Atopic Neurodermatitis Besnier'S Prurigo Dermatitis, Atopic, 1 Dermatitis Atopic Eczema Besnier Prurigo
Colorectal Cancer	Colon Cancer Colorectal Carcinoma Colon Carcinoma Colorectal Cancer, Susceptibility To Carcinoma Of Colon CRC Colorectal Cancer With Chromosomal Instability, Somatic Colon Cancer, Somatic Colon Cancer, Susceptibility To Colonic Neoplasms Colorectal Neoplasms Colorectal Cancer, Somatic Colon Cancer, Advanced, Somatic Colonic Carcinoma Colorectal Carcinomas Colon Cancers Colorectal Cancers Cancer, Colorectal, Somatic Cancer, Colon Cancer, Colorectal, Susceptibility To Colorectal Neoplasm Colonic Neoplasm Malignant Tumor Of Colon
Leukocyte Disease	Leukocyte Disorders
Combined Immunodeficiency	Combined T Cell And B Cell Immunodeficiency Congenital Combined Immunodeficiency Syndrome With Combined Immunodeficiency Combined T And B Cell Immunodeficiency Combined Immunity Deficiency Combined Immunodeficiency Syndrome Combined T-Cell And B-Cell Immunodeficiency Lymphopenic Agammaglobulinaemia
Coronavirus Infectious Disease
Oxirane Allergy	Ethylene Oxide Allergy Eto Allergy
Developmental And Epileptic Encephalopathy 38	DEE38 Epileptic Encephalopathy, Early Infantile, 38 Eiee38 Developmental And Epileptic Encephalopathy, 38 Glycosylphosphatidylinositol Biosynthesis Defect 23 Gpibd23 Early Infantile Epileptic Encephalopathy 38
Hemophagocytic Lymphohistiocytosis	Lymphohistiocytosis, Hemophagocytic Haemophagocytic Syndrome Lymphohistiocytosis Hemophagocytic Hemophagocytic Syndrome Familial Hemophagocytic Lymphocytosis Histiocytoses Of Mononuclear Phagocytes Haemophagocytic Lymphohistiocytosis Nos
Immune Deficiency Disease	Immunodeficiency Primary Immunodeficiency Primary Immunodeficiency Disease Immunologic Deficiency Syndromes Hypoimmunity Immune Deficiency Disorder Immunodeficiency Syndrome Immune Disorder Primary Immune Deficiency Disorder Immune System Diseases Human Immunodeficiency Virus Infection Hiv - [Human Immunodeficiency Virus Infection] Hiv Positive Nos Hiv Disease Acquired Immune Deficiency Syndrome-Related Complex Aids-Like Syndrome Aids-Related Complex Nos Arc - [Aids-Related Complex] Immunodeficiency Due To Human Immunodeficiency Virus Infection Unspecified Human Immunodeficiency Virus Disease Hiv Disease Nos Human Immunodeficiency Virus Positive Nos Hiv Nos Deficiency Of Complement Initial Pathway Deficiency Of Complement Terminal Pathway Cfdd - [Complement Factor D Deficiency] Immunodeficiency With Nk-Cell - [Natural-Killer Cell] Deficiency Nonfamilial Hypogammaglobulinaemia Common Variable Immune Deficiency Nonfamilial Agammaglobulinaemia Common Variable Agammaglobulinaemia Agammaglobulinaemia Nos Agammaglobulinaemia Antibody Deficiency Syndrome Hypogammaglobulinaemia Antibody Deficiency Syndrome Acquired Agammaglobulinaemia Nos Hypogammaglobulinaemia Nos Hyper Igm
Immunodeficiency 55	Combined Immunodeficiency Due To Gins1 Deficiency IMD55 Cid Due To Gins1 Deficiency Combined Immunodeficiency With Intrauterine Growth Retardation-Nk Cell Deficiency-Neutropenia Combined Immunodeficiency With Intrauterine Growth Retardation-Natural Killer Cell Deficiency-Neutropenia
Bronchiectasis 3
Lipoprotein Quantitative Trait Locus	Coronary Artery Disease Coronary Artery Anomaly Coronary Artery Disease, Susceptibility To Myocardial Ischemia Congenital Anomaly Of Coronary Artery Coronary Arteriosclerosis Coronary Disease Coronary Heart Disease Coronary Artery Disorder LPAQTL Lpa Deficiency, Congenital Coronary Artery Abnormality Coronary Artery Anomaly, Congenital Chd Coronary Syndrome Congenital Malformations Of Coronary Vessels Malformation Of Coronary Vessels Congenital Coronary Artery Anomaly Congenital Coronary Artery Deformity Congenital Coronary Artery Disorder Abnormal Coronary Artery Congenital Coronary Artery Malposition Congenital Coronary Disease Congenital Anomaly Of Coronary Arteries
Dermatitis, Atopic, 5	ATOD5 Atopic Dermatitis 5 Dermatitis, Atopic, Susceptibility To, 5 Dermatitis, Atopic 5
Blood Platelet Disease	Platelet Disorder Blood Platelet Disorders Thrombocytopathy Platelet Dysfunction Platelet Disorders Qualitative Platelet Deficiency
Behcet Syndrome	Behcet Disease Behcet'S Syndrome Behcet'S Disease Behçet Disease Bd Adamantiades-Behcet Disease Triple Symptom Complex Behçet'S Disease Behet'S Syndrome Bd Syndrome Behçet Syndrome Behçet'S Syndrome Behcet Triple Symptom Complex Malignant Aphthosis Old Silk Route Disease Adamantiades-Behçet Disease
Leukemia, Acute Myeloid	Acute Myeloid Leukemia Leukemia, Acute Myelogenous Acute Myelogenous Leukemia AML Leukemia, Acute Myeloid, Susceptibility To Acute Myeloblastic Leukemia Leukemia, Acute Myeloid, Reduced Survival In, Somatic Acute Myeloid Leukaemia Leukemia, Myelocytic, Acute Therapy Related Acute Myeloid Leukemia And Myelodysplastic Syndrome Secondary Aml Acute Myelocytic Leukemia Acute Myeloid Leukemia, Somatic Leukemia, Acute Myeloid, Somatic Myeloid Leukemia, Acute, M4/M4eo Subtype, Somatic Acute Myeloblastic Leukaemia Acute Myelogenous Leukaemia Aml - Acute Myeloid Leukemia Acute Myeloid Leukemia With Cebpa Somatic Mutations Aml With Cebpa Somatic Mutations Inherited Acute Myeloid Leukemia Familial Aml Inherited Aml Pure Familial Aml Pure Familial Acute Myeloid Leukemia Secondary Acute Myeloid Leukemia Therapy-Related Aml And Myelodysplastic Syndrome Acute Myeloid Leukemia, Secondary Acute Non-Lymphoblastic Leukemia Acute Non-Lymphocytic Leukemia Acute Biphenotypic Leukemia Acute Undifferentiated Leukemia Acute Myeloblastic Leukaemia With Multilineage Dysplasia Acute Myeloid Leukaemia With Multilineage Dysplasia Without Mention Of Remission Acute Myeloid Leukaemia With Myelodysplasia-Related Features
Skin Disease	Skin Diseases Genodermatosis Abnormality Of The Skin Skin Diseases, Genetic Skin And Subcutaneous Tissue Disease Dermatologic Disorders
Leukemia, Chronic Lymphocytic	Chronic Lymphocytic Leukemia B-Cell Chronic Lymphocytic Leukemia CLL B-Cell Chronic Lymphoid Leukemia Chronic Lymphatic Leukemia Chronic Lymphocytic Leukaemia Lymphoplasmacytic Leukemia Small Lymphocytic Lymphoma Leukemia, Chronic Lymphatic B-Cell Chronic Lymphocytic Leukaemia Chronic Lymphatic Leukaemia Lymphoplasmacytic Leukaemia B Cell Chronic Lymphocytic Leukemia Chronic B-Cell Lymphocytic Leukemia Leukemia, Lymphocytic, Chronic B-Cll Chronic Lymphoid Leukemia Leukemia Lymphocytic Chronic Lymphoma Small Lymphocytic Leukemia, Lymphocytic, Chronic, B-Cell
Connective Tissue Disease	Connective Tissue Diseases Connective Tissue Disorder Abnormality Of Connective Tissue Disorder Of Connective Tissue Connective Tissue Disorders
Nervous System Disease	Abnormality Of The Nervous System Nervous System Diseases Nervous System Disorder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS04831	FCGR3A Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS04832	FCGR3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS23733	Fcgr2a Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS24567	Fcgr3a Rat Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	FCGR3A	MGD	MGI:2179523
Rattus norvegicus	FCGR3A	RGD	RGD:1303067