Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)
Based on 1 Customer Validation
Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) is an anti-mouse Thy1/CD90 IgG2a monoclonal antibody. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can clear T cells from the spleen and bone marrow. Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) can be used for researches on immunology and inflammation conditions such as colitis.
For research use only. We do not sell to patients.
- Purity: 95.00%
- Molecular Weight:150 kDa
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Isotype
Rat IgG2a kappa
Recommend Isotype Controls
Species Reactivity
Mouse
IC50 & Target
Thy1/CD90
In Vitro
Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) (50 μg/mL, 1 h) can remove T cells combined with 1:20 rabbit complement in antigen-presenting cells (APCs) from the spleen of mice[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:CD40 mAb induced Rag2−/−Il2rg−/− mice (8-16 weeks)[3]
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Dosage:250 μg
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Administration:Intraperitoneal injection (i.p.), on days −1, 1 and 4
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Result:Cleared innate lymphocytes (including NKR LTi cells, LTi like cells, and NK cells).
Relieved colitis symptoms.
Gene ID
Accession
Conjugated
Unconjugated
Reconsititution
The product can be reconstituted/diluted with sterile PBS or saline.
Format
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Product Image
Application
in vitro T cell depletion
Chemical Information
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Appearance Liquid
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Molecular Weight 150 kDa
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Color Colorless to light yellow
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SMILES
[Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1)]
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Data Sheet (261 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Inhibitory Antibodies User Guide (603 KB)
References
[1]. Weng X, et al. The adaptor protein SAP regulates type II NKT-cell development, cytokine production, and cytotoxicity against lymphoma. Eur J Immunol. 2014 Dec;44(12):3646-57. [Content Brief]
[2]. Jenkins BJ, et al. ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity. bioRxiv [Preprint]. 2025 Mar 19:2025.03.19.643996. [Content Brief]
[3]. Vonarbourg C, et al. Regulated expression of nuclear receptor RORγt confers distinct functional fates to NK cell receptor-expressing RORγt(+) innate lymphocytes. Immunity. 2010 Nov 24;33(5):736-51. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Anti-Mouse Thy1/CD90 Antibody (M5/49.4.1) Related Classifications
HY-P990157 Related Classifications
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