Anti-Rat CD4 Antibody (W3/25)

製品番号: HY-P991762: Data Sheet
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Anti-Rat CD4 Antibody (W3/25) reacts with rat CD4. Anti-Rat CD4 Antibody (W3/25) inhibits CD4+ T cell activation by downregulating the CD4 molecule on the surface of lymphocytes. Anti-Rat CD4 Antibody (W3/25) inhibits antigen-induced T cell proliferation and IL2 production in MLR experiments. Anti-Rat CD4 Antibody (W3/25) can be used for the study of experimental allergic encephalomyelitis (EAE). Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977).

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Anti-Rat CD4 Antibody (W3/25) 構造式

容量		在庫状況
MOQ		Minimum order quantity
1 mg		お問い合わせ
5 mg		お問い合わせ
10 mg		お問い合わせ
Other size		お問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

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製品説明	Anti-Rat CD4 Antibody (W3/25) reacts with rat CD4. Anti-Rat CD4 Antibody (W3/25) inhibits CD4+ T cell activation by downregulating the CD4 molecule on the surface of lymphocytes. Anti-Rat CD4 Antibody (W3/25) inhibits antigen-induced T cell proliferation and IL2 production in MLR experiments. Anti-Rat CD4 Antibody (W3/25) can be used for the study of experimental allergic encephalomyelitis (EAE). Recommend Isotype Controls: Mouse IgG1 kappa, Isotype Control (HY-P99977)^[1]^[2]^[3]^[4].
Isotype	Mouse IgG1 kappa
Recommend Isotype Controls	Mouse IgG1 kappa, Isotype Control
Species Reactivity	Rat
IC₅₀ & Target	CD4
Gene ID	24932 [NCBI]
Accession	P05540
Application	in vivo down-regulation of surface CD4; in vitro neutralization of CD4; Flow cytometry; Immunohis
Conjugated	Unconjugated
Reconsititution	The product can be reconstituted/diluted with sterile PBS or saline.
Formulation	Please refer to the lot-specific COA for specific buffer information.
保管条件	Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション	データシート (256 KB) Inhibitory Antibodies User Guide (603 KB)
参考文献	[1]. Acroute DV, et al. A role for CD4+ and CD8+ cells and not for CD25+ cells in the control of Plasmodium berghei Anka blood stage parasites in rats. Parasite. 2010 Mar;17(1):53-60. [Content Brief] [2]. Mannie MD, et al. MHC class-II-restricted antigen presentation by myelin basic protein-specific CD4+ T cells causes prolonged desensitization and outgrowth of CD4- responders. Cell Immunol. 2001 Aug 25;212(1):51-62. [Content Brief]