country

Change Language

Country or Region:

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-P84025A

ACAA1 Antibody (YA3722)(PBS only)

Name: ACAA1 Antibody (YA3722)(PBS only)
Brand: MedChemExpress
SKU: HY-P84025A
Availability: PreOrder

(Synonyms: ACAA; THIO; PTHIO)

ACAA1 Antibody (YA3722) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACAA1.

For research use only. We do not sell to patients.

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications

Application	WB WB: Western Blot	IHC-P IHC-P: Immunohistochemistry-Paraffin	FC FC: Flow Cytometry	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:500-1:2000	1:200-1:1000	1:200-1:400	1:10000

Description

ACAA1 Antibody (YA3722) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ACAA1.

Host Mouse
Species Reactivity
Human, Mouse
Observed Molecular Weight

Observed band size: 44 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 44 kDa

Immunogen

Purified recombinant fragment of human ACAA1(AA: 217-315) expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG1

Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Function

ACAA1 is responsible for the thiolytic cleavage of straight chain 3-keto fatty acyl-CoAs (3-oxoacyl-CoAs). Plays an important role in fatty acid peroxisomal beta-oxidation. Catalyzes the cleavage of short, medium, long, and very long straight chain 3-oxoacyl-CoAs^[1]^[2].
Subcellular Localization

Peroxisome
Expression

Induction:Peroxisomal thiolase is markedly induced (at the level of transcription) by various hypolipidemic compounds in parallel with the other two enzymes of the peroxisomal beta-oxidation system
Isoforms & Post-Translational Modification

P09110 has 2 isomers: P09110-1: 44292 Da (predicted); P09110-2: 34665 Da (predicted).
Subunit

Homodimer (Ref.16). Interacts (via PTS2-type peroxisomal targeting signal region) with PEX7; leading to its translocation into peroxisomes (PubMed:22057399, PubMed:25538232)
SwissProt ID

P09110
Gene ID

30 [NCBI]
Synonyms

ACAA; THIO; PTHIO