ALDH1A3 Antibody (YA7752)
(Synonyms: ALDH1A6; ALDH6; MCOP8; RALDH3)ALDH1A3 Antibody (YA7752) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ALDH1A3.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC
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Reactivity :
Human, Dog, Monkey, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100 |
Product Details
ALDH1A3 Antibody (YA7752) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ALDH1A3.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Dog, Monkey, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 55.9 kDa
Human recombinant protein fragment corresponding to amino acids 1-100 and 413-512 of human ALDH1A3 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ALDH1A3 catalyzes the NAD-dependent oxidation of aldehyde substrates, such as all-trans-retinal and all-trans-13,14-dihydroretinal, to their corresponding carboxylic acids, all-trans-retinoate and all-trans-13,14-dihydroretinoate, respectively. High specificity for all-trans-retinal as substrate, can also accept acetaldehyde as substrate in vitro but with lower affinity. Required for the biosynthesis of normal levels of retinoate in the embryonic ocular and nasal regions; a critical lipid in the embryonic development of the eye and the nasal region[1].
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Subcellular Localization
Cytoplasm
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Expression
Tissue_Specificity: Expressed at low levels in many tissues and at higher levels in salivary gland, stomach, and kidney -
Isoforms & Post-Translational Modification
P47895: 512 amino acids, molecular weight 56108 Da.
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Subunit
Homotetramer
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SwissProt ID
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Synonyms
ALDH1A6; ALDH6; MCOP8; RALDH3
Documentation
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