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ASCC1 Antibody (YA8397)(PBS only)

(Synonyms: ASC1p50; CGI-18; RP11-150D20.4)

ASCC1 Antibody (YA8397) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASCC1.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG1

  • Application:

    IHC-P, ICC/IF, FC

  • Reactivity :

    Human, Mouse, Rat

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
  • ASCC1 Antibody (YA8397)(PBS only) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
IHC-P Info
IHC-P: Immunohistochemistry-Paraffin
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
FC Info
FC: Flow Cytometry
Dilution Ratio 1:150-500 1:100-250 1:100

Product Details

Description

ASCC1 Antibody (YA8397) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to ASCC1.

  • Host Mouse
  • Species Reactivity
    Human, Mouse, Rat
  • Calculated Molecular Weight Predicted band size: 41 kDa
Immunogen

Full length human recombinant protein of human ASCC1 produced in HEK293T cell.

Purification

Affinity purified

Conjugation

Non-conjugated

Isotype

IgG1

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    ASCC1 plays a role in DNA damage repair as component of the ASCC complex. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. In cells responding to gastrin-activated paracrine signals, it is involved in the induction of SERPINB2 expression by gastrin. May also play a role in the development of neuromuscular junction[1][2].

  • Subcellular Localization

    Nucleus,Nucleus speckle

  • Expression


    Tissue_Specificity: Ubiquitous

  • Isoforms & Post-Translational Modification

    Q8N9N2 has two isomers: Q8N9N2-1: 45509 Da (predicted); Q8N9N2-2: 41228 Da (predicted).

  • Subunit

    Identified in the ASCC complex that contains ASCC1, ASCC2 and ASCC3 (PubMed:29144457, PubMed:29997253)

  • SwissProt ID

    Q8N9N2

  • Synonyms

    ASC1p50; CGI-18; RP11-150D20.4

ASCC1 Antibody (YA8397)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • ASCC1 Antibody (YA8397)(PBS only) Product Image