ASGPR1 Antibody (YA1298)
(Synonyms: ASGP-R 1, HL-1, CLEC4H1, ASGPR1, ASGPR)ASGPR1 Antibody (YA1298) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ASGPR1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP, FC, IF-Tissue
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Reactivity :
Human, Rat
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|---|
| Dilution Ratio | 1:1,000 | 1:100 | 1:4,000 | 1:1,000 | 1:1,000 | 1-2μg/sample |
Product Details
ASGPR1 Antibody (YA1298) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ASGPR1.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size:40-50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 33 kDa
Recombinant protein within human ASGPR1 aa 41-291.
Endogenous
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
ASGPR1 mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface
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Subcellular Localization
Membrane; Single-pass type II membrane protein; Secreted
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Expression
Tissue_specificity:Expressed exclusively in hepatic parenchymal cells -
Isoforms & Post-Translational Modification
P07306 has 2 isomers: P07306-1: 33186 Da (predicted); P07306-2: 29144 Da (predicted).
Phosphorylated on a cytoplasmic Ser residue -
Subunit
Interacts with LASS2
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SwissProt ID
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Synonyms
ASGP-R 1, HL-1, CLEC4H1, ASGPR1, ASGPR
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Research Field
Cell biology
Documentation
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