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  4. Monoclonal Antibodies Recombinant Antibodies
  5. ATP Synthase C Antibody (YA2205)

ATP Synthase C Antibody (YA2205)

Cat. No.: HY-P82460
User Guide for Antibodies Technical Support

ATP Synthase C Antibody (YA2205) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATP Synthase C.

For research use only. We do not sell to patients.

Size Price Stock Quantity
20 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   Get quote  
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

Description

ATP Synthase C Antibody (YA2205) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ATP Synthase C.
Host

Rabbit
Clonality

Recombinant, Monoclonal
Molecular Weight
Predicted band size: 14 kDa;
Observed band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Rat
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human ATP5G1/G2/G3 aa 98-110.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：P05496: Subunit c, of the mitochondrial membrane ATP synthase complex (F (1) F (0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain (Probable). ATP synthase complex consist of a soluble F (1) head domain - the catalytic core - and a membrane F (1) domain - the membrane proton channel (PubMed:37244256). These two domains are linked by a central stalk rotating inside the F (1) region and a stationary peripheral stalk (PubMed:37244256). During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). With the subunit a (MT-ATP6) , forms the proton-conducting channel in the F (0) domain, that contains two crucial half-channels (inlet and outlet) that facilitate proton movement from the mitochondrial intermembrane space (IMS) into the matrix (PubMed:37244256).
Q06055: Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1) - containing the extramembraneous catalytic core and F (0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F (0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element
P48201: Mitochondrial membrane ATP synthase (F (1) F (0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F (1) - containing the extramembraneous catalytic core and F (0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F (1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F (0) domain. A homomeric c-ring of probably 10 subunits is part of the complex rotary element
Subcellular Localization：P05496: Mitochondrion membrane; Multi-pass membrane protein
Q06055: Mitochondrion membrane; Multi-pass membrane protein
P48201: Mitochondrion membrane; Multi-pass membrane protein
Isoforms & Post-Translational Modification：Q06055 has 3 isomers: Q06055-1: 14637 Da (predicted); Q06055-2: 20513 Da (predicted); Q06055-3: 16334 Da (predicted).
Trimethylated by ATPSCKMT at Lys-109. Methylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration
Subunit：P05496: Homooctamer; the c-ring consists of eight c subunits forming a circle, and each subunit adopts a hairpin shape (PubMed:37244256).
Q06055: F-type ATPases have 2 components, CF (1) - the catalytic core - and CF (0) - the membrane proton channel. CF (1) has five subunits: alpha (3) , beta (3) , gamma (1) , delta (1) , epsilon (1). CF (0) has three main subunits: a, b and c (PubMed:8328972). Interacts with DNAJC30; interaction is direct (PubMed:30318146)
P48201: F-type ATPases have 2 components, CF (1) - the catalytic core - and CF (0) - the membrane proton channel. CF (1) has five subunits: alpha (3) , beta (3) , gamma (1) , delta (1) , epsilon (1). CF (0) has three main subunits: a, b and c. Interacts with TMEM70 and TMEM242 (PubMed:33753518)
Database

Entrez Gene: 516 Human ; 517 Human ; 518 Human

SwissProt: P05496 Human ; Q06055 Human ; P48201 Human ;

OMIM: 603192 Human

Research Field

Signal Transduction
Synonyms
ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1
Documentation
User Guide for Antibodies (1077 KB)

ATP Synthase C Antibody (YA2205) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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