ATP5MC3 - ATP synthase membrane subunit c locus 3 Gene

Also Known as P3; ATP5G3; DYTSPG

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 518

Summary

This gene encodes a subunit of mitochondrial ATP Synthase. Mitochondrial ATP Synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during Oxidative Phosphorylation. ATP Synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP Synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the Other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]

ATP5MC3 Products (1)

mRNA Protein Name
NM_001002256.1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
33753518 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP synthase F(0) complex subunit C3, mitochondrial

  • ATP synthase lipid-binding protein, mitochondrial

  • ATP synthase proteolipid P3

  • ATP synthase proton-transporting mitochondrial F(0) complex subunit C3

  • ATP synthase subunit 9

  • ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)

ATP5MC3 Antibodies

Cat. No. Product Name Application Reactivity
HY-P82460 ATP Synthase C Antibody (YA2205) WB, IHC-P, IP Human, Rat
HY-P82460A ATP Synthase C Antibody (YA2205)(PBS only) WB, IHC-P, IP Human, Rat

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01208 ATP5MC1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown