BID Antibody (YA7577)

Cat. No.: HY-P87892: Data Sheet COA
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User Guide for Antibodies
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BID Antibody (YA7577) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to BID.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

BID Antibody (YA7577) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to BID.

Host

Rabbit

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 22 kDa;

Observed band size: 22 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P55957

Immunogen

The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000-1:4000
WB WB: Western Blot	1:2000-1:10000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-1:20000
IP IP: Immunoprecipitation	1:50-1:200

Sensitivity	Endogenous	Purity	Protein A affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG,Kappa

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity)|Induces caspase activation and apoptosis (PubMed:15661737, PubMed:32029622). Allows the release of cytochrome c (PubMed:32029622)|Induces ICE-like proteases and apoptosis|Induces ICE-like proteases and apoptosis|Does not induce apoptosis|Induces ICE-like proteases and apoptosis

Subcellular Localization：Cytoplasm,Mitochondrion membrane,Mitochondrion outer membrane,Mitochondrion membrane,Mitochondrion membrane,Cytoplasm,Cytoplasm,Mitochondrion membrane

Expression：
Tissue_Specificity: Expressed in spleen, pancreas and placenta (at protein level)|Expressed in lung, pancreas and spleen (at protein level)|Expressed in lung and pancreas (at protein level)

Isoforms & Post-Translational Modification：P55957 has four isomers: P55957-1: 21995 Da (predicted); P55957-2: 26836 Da (predicted); P55957-3: 14620 Da (predicted); P55957-4: 11263 Da (predicted).
TNF-alpha induces caspase-mediated cleavage into a major p15 and minor p13 and p11 products (By similarity)丨Ubiquitinated by ITCH; ubiquitination results in proteasome-dependent degradation

Subunit：Forms heterodimers either with the pro-apoptotic protein BAX or the anti-apoptotic protein BCL2 (By similarity)

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)