CADM2 Antibody
(Synonyms: IGSF4D, NECL3, CADM2, Cell adhesion molecule 2, Immunoglobulin superfamily member 4D, Nectin-like protein 3, Synaptic cell adhesion molecule 2, IgSF4D, NECL-3, SynCAM 2)CADM2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CADM2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:100-500 |
Product Details
CADM2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to CADM2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 48 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 47 kDa
Synthetic peptide corresponding to the center region of human CADM2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CADM2 is an Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes
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Subcellular Localization
Cell membrane; Synapse; Cell projection, axon
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Isoforms & Post-Translational Modification
CADM2 has 5 isoforms, Q8N3J6-1: amino acid length is 435, molecular weight is 47554 Da (predicted); Q8N3J6-2: amino acid length is 404, molecular weight is 44423 Da (predicted); Q8N3J6-3: amino acid length is 437, molecular weight is 47564 Da (predicted); Q8N3J6-4: amino acid length is 287, molecular weight is 31382 Da (predicted); Q8N3J6-5: amino acid length is 327, molecular weight is 35410 Da (predicted).
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Subunit
Interacts with the palmitolyated form of CADM4
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SwissProt ID
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Synonyms
IGSF4D, NECL3, CADM2, Cell adhesion molecule 2, Immunoglobulin superfamily member 4D, Nectin-like protein 3, Synaptic cell adhesion molecule 2, IgSF4D, NECL-3, SynCAM 2
Documentation
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