Calpain 1 Antibody (YA3687)
(Synonyms: CANP; muCL; CANP1; SPG76; CANPL1; muCANP)Calpain 1 Antibody (YA3687) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Calpain 1.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, IHC-P, FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
Calpain 1 Antibody (YA3687) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to Calpain 1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 75 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 82 kDa
Purified recombinant fragment of human CAPN1 (AA: 501-714) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Calpain 1 is a Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves CTBP1 at 'Asn-375', 'Gly-387' and 'His-409'. Cleaves and activates caspase-7 (CASP7)[1][2][3][4].
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Subcellular Localization
Cytoplasm; Cell membrane
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Expression
Tissue_specificity:general expression -
Subunit
Forms a heterodimer with a small (regulatory) subunit CAPNS1
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SwissProt ID
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Synonyms
CANP; muCL; CANP1; SPG76; CANPL1; muCANP
Documentation
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