Caspase 12/ CASP12 Antibody
(Synonyms: UNQ9415/PRO34398, CASP12, Inactive caspase-12, CASP-12)Caspase 12 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Caspase 12.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
Caspase 12 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Caspase 12.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 55 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 38 kDa
Synthetic peptide corresponding to the center region of human Caspase 12.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Caspase 12/ CASP12 may function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF. May lack protease activity (Probable)[1].
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Expression
Tissue_Specificity: Widely expressed, with highest levels in lung. -
Isoforms & Post-Translational Modification
Caspase 12/ CASP12 has 8 isoforms, Q6UXS9-1: amino acid length is 341, molecular weight is 38907 Da (predicted); Q6UXS9-2: amino acid length is 168, molecular weight is 19136 Da (predicted); Q6UXS9-3: amino acid length is 142, molecular weight is 16181 Da (predicted); Q6UXS9-4: amino acid length is 277, molecular weight is 31064 Da (predicted); Q6UXS9-5: amino acid length is 295, molecular weight is 33628 Da (predicted); Q6UXS9-6: amino acid length is 224, molecular weight is 25103 Da (predicted); Q6UXS9-7: amino acid length is 226, molecular weight is 25659 Da (predicted); Q6UXS9-8: amino acid length is 140, molecular weight is 15625 Da (predicted).
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SwissProt ID
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Synonyms
UNQ9415/PRO34398, CASP12, Inactive caspase-12, CASP-12
Documentation
References
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