CCNB1IP1 Antibody (YA7865)
(Synonyms: C14orf18; HEI10)
Based on 1 Customer Validation
CCNB1IP1 Antibody (YA7865) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCNB1IP1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:150-500 | 1:100 |
Product Details
CCNB1IP1 Antibody (YA7865) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CCNB1IP1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 31.4 kDa
Full length human recombinant protein of human CCNB1IP1 produced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Solution
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CCNB1IP1 is an Ubiquitin E3 ligase that acts as a limiting factor for crossing-over during meiosis: required during zygonema to limit the colocalization of RNF212 with MutS-gamma-associated recombination sites and thereby establish early differentiation of crossover and non-crossover sites. Later, it is directed by MutL-gamma to stably accumulate at designated crossover sites. Probably promotes the dissociation of RNF212 and MutS-gamma to allow the progression of recombination and the implementation of the final steps of crossing over. Modulates cyclin-B levels and participates in the regulation of cell cycle progression through the G2 phase. Overexpression causes delayed entry into mitosis
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Subcellular Localization
Nucleus,Chromosome
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Expression
Tissue_Specificity: Highly expressed in heart. Detected at intermediate levels in liver and kidney, and at low levels in placenta, brain and lung -
Isoforms & Post-Translational Modification
Q9NPC3: 277 amino acids, molecular weight 31544 Da.
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Subunit
Interacts with CCNB1, UBE2L3 and NF2
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SwissProt ID
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Synonyms
C14orf18; HEI10
Documentation
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