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CD186 Antibody (YA3493)

(Synonyms: CXCR6; BONZO; CDw186; STRL33; TYMSTR)
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Based on 1 Customer Validation

CD186 Antibody (YA3493) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD186.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG

  • Application:

    WB, FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS with 0.05% sodium azide

  • Conjugation:
    Non-conjugated
  • Experimental Validation Results for CD186 Antibody (YA3493)
  • CD186 Antibody (YA3493) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:500-1:2000 1:200-1:400 1:10000

Product Details

Description

CD186 Antibody (YA3493) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD186.

  • Host Mouse
  • Clonality Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 39 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 39 kDa
Immunogen

Purified recombinant fragment of human CD186 expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3718768

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS with 0.05% sodium azide

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Verification Images

  • Experimental Validation Results for CD186 Antibody (YA3493)
    Western blot analysis of extracts from Hela (lane 2(20μg)

Background

  • Function

    CD186 receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1

  • Subcellular Localization

    Cell membrane; Multi-pass membrane protein

  • Expression


    Tissue_specificity:Expressed in lymphoid tissues and activated T cells

  • SwissProt ID

    O00574

  • Gene ID
    10663 [NCBI]
  • Synonyms

    CXCR6; BONZO; CDw186; STRL33; TYMSTR

CD186 Antibody (YA3493) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • 1/16

    MedChemExpress Validation
     Western blot analysis of extracts from Hela (lane 2(20μg)

  • CD186 Antibody (YA3493) Product Image
    1/16
  • Experimental Validation Results for CD186 Antibody (YA3493)
  • CD186 Antibody (YA3493) Product Image
  • Experimental Validation Results for CD186 Antibody (YA3493)
    1/1
    MedChemExpress Validation
     Western blot analysis of extracts from Hela (lane 2(20μg)
  • Experimental Validation Results for CD186 Antibody (YA3493)
  • CD186 Antibody (YA3493) Product Image
    MedChemExpress Validation

    Western blot analysis of extracts from Hela (lane 2(20μg)

  • CD186 Antibody (YA3493) Product Image WB