CD23 Antibody (YA1296)
(Synonyms: BLAST-2, CD23A, CLEC4J, FCE2, IGEBF)CD23 Antibody (YA1296) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD23.
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Host:
Rabbit
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Isotype:
IgG
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, Glycerol and BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P-1
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 50-1:100 | 1:50-1:100 | 1:50-1:100 |
Product Details
CD23 Antibody (YA1296) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD23.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 36 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 36 kDa
Peptide
Endogenous
Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, Glycerol and BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CD23 is a Low-affinity receptor for immunoglobulin E (IgE) and CR2/CD21. Has essential roles in the regulation of IgE production and in the differentiation of B cells. On B cells, initiates IgE-dependent antigen uptake and presentation to T cells. On macrophages, upon IgE binding and antigen cross-linking induces intracellular killing of parasites through activation of L-Arginine-nitric oxide pathway[1][2].
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Subcellular Localization
Cell membrane; Single-pass type II membrane protein; Cell membrane; Lipid-anchor; Secreted
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Expression
Tissue_specificity:Protein levels were detected in the urine. -
Subunit
Homotrimer. Interacts (via C-type lectin domain) with IGHE (via CH3 region); this interaction regulates IgE homeostasis. Interacts (via the C-terminus) with CR2/CD21 (via Sushi domain 1 and 2) (PubMed:1386409, PubMed:16172256)
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SwissProt ID
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Synonyms
BLAST-2, CD23A, CLEC4J, FCE2, IGEBF
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Research Field
Immunology
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