CD72 Antibody (YA4698)

Cat. No.: HY-P85006: Data Sheet User Guide for Antibodies
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CD72 Antibody (YA4698) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD72.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

CD72 Antibody (YA4698) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CD72.

Host

Mouse

Clonality

Monoclonal

Species Reactivity

Human

SwissProt ID

P21854

Gene ID

971 [NCBI]

Immunogen

Purified recombinant Human CD72

Application &
Dilution Ratio

Application	Dilution Ratio
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-100000
FC FC: Flow Cytometry	1-2μg/Test

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in Phosphate-buffered solution.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Co-receptor of B cell receptor (BCR) that plays both positive and negative roles on B-cell functions. Recognizes the Sm/ribonucleoprotein (RNP) self-antigen ligand, and coligation of CD72 and BCR inhibits BCR signaling. Mechanistically, ligand binding leads to the recruitment of PTPN6/SHP-1 to the BCR complex which is inhibitory to BCR signaling. Also acts as a ligand for CD5 and thereby plays a critical role in maintaining regulatory T and B-cell homeostasis

Subcellular Localization：Membrane; Single-pass type II membrane protein

Expression：
Tissue_specificity:Pre-B-cells and B-cells but not terminally differentiated plasma cells

Subunit：Homodimer; disulfide-linked. Associates with CD5. Interacts (tyrosine phosphorylated) with PTPN6/SHP-1

Synonyms

CD72; B-cell differentiation antigen CD72; Lyb-2; CD72; CD72 nanobody;

Documentation

User Guide for Antibodies (1077 KB)