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CDX1 Antibody (YA1962)

(Synonyms: CDX1; Homeobox protein CDX 1)
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CDX1 Antibody (YA1962) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDX1.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, ICC/IF

  • Reactivity :

    Human

  • Formulation:

    Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Conjugation:
    Non-conjugated
  • CDX1 Antibody (YA1962) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
WB Info
WB: Western Blot
ICC/IF Info
ICC/IF: Immunocytochemistry/
Immunofluorescence
Dilution Ratio 1:500-1:1000 1:50-1:200

Product Details

Description

CDX1 Antibody (YA1962) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDX1.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 28 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 28 kDa
Species Reactivity Database

Entrez Gene: 1044 Human

SwissProt: P47902 Human

Immunogen

A synthesized peptide derived from human Cdx1 aa1-49/265.

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3104330

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    CDX1 plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA[1][2].

  • Subcellular Localization

    Nucleus

  • Expression


    Tissue_specificity:intestinal epithelium

  • Isoforms & Post-Translational Modification

    P47902 has 2 isomers: P47902-1: 28138 Da (predicted); P47902-2: 14661 Da (predicted).

  • SwissProt ID

    P47902

  • Gene ID
    1044 [NCBI]
  • Synonyms

    CDX1; Homeobox protein CDX 1

  • Research Field

    Epigenetics and Nuclear Signaling

CDX1 Antibody (YA1962) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • CDX1 Antibody (YA1962) Product Image
    1/16
  • CDX1 Antibody (YA1962) Product Image