Claudin 10 Antibody
(Synonyms: Claudin-10, Oligodendrocyte-specific protein-like, OSP-like, CLDN10)Claudin 10 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Claudin 10.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
Claudin 10 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Claudin 10.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 24 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 24 kDa
Synthetic peptide corresponding to the C-term region of human Claudin 10.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Claudin 10 forms paracellular channels: polymerizes in tight junction strands with cation- and anion-selective channels through the strands, conveying epithelial permeability in a process known as paracellular tight junction permeability
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Subcellular Localization
Cell junction, tight junction; Cell membrane
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Expression
Tissue_Specificity: Expressed in the kidney, eccrine sweat glands and in all layers of the epidermis. In the kidney, it is detected in the thick ascending limb of Henle's loop (TAL). In the sweat glands, it is expressed in cells from secretory portions, corresponding to the clear cells. -
Isoforms & Post-Translational Modification
Claudin 10 has 3 isoforms, P78369-1: amino acid length is 228, molecular weight is 24488 Da (predicted); P78369-2: amino acid length is 226, molecular weight is 24251 Da (predicted); P78369-3: amino acid length is 207, molecular weight is 22167 Da (predicted).
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Subunit
Can form homodimers both in trans (interaction between CLDN10 molecules in opposing membranes) and in cis (interaction between CLDN10 molecules within one membrane)
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SwissProt ID
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Synonyms
Claudin-10, Oligodendrocyte-specific protein-like, OSP-like, CLDN10
Documentation
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