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  4. Monoclonal Antibodies Recombinant Antibodies
  5. Cyclin E2 Antibody (YA2594)(PBS only)

Cyclin E2 Antibody (YA2594)(PBS only)

Cat. No.: HY-P82849A
User Guide for Antibodies Technical Support

Cyclin E2 Antibody (YA2594) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclin E2.

For research use only. We do not sell to patients.

Size Stock
50 μL   Get quote  
100 μL   Get quote  

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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • Documentation

  • References

Description

Cyclin E2 Antibody (YA2594) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Cyclin E2.
Host

Rabbit
Molecular Weight
Predicted band size: 47 kDa;
Observed band size: 47 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human Cyclin E2
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IHC-P
IHC-P: Immunohistochemistry-Paraffin
1:50-1:100
IHC-F
IHC-F: Immunohistochemistry-Frozen
1:50-1:100
ICC/IF
ICC/IF: Immunocytochemistry/Immunofluorescence
1:50-1:200
Purity Affinity Purified Conjugation Non-conjugated
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in PBS, pH 7.4.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.
Background
Function：Essential for the control of the cell cycle at the late G1 and early S phase
Subcellular Localization：Nucleus
Expression：
Tissue_specificity:According to PubMed:9858585, highest levels of expression in adult testis, thymus and brain. Lower levels in placenta, spleen and colon. Consistently elevated levels in tumor-derived cells compared to non-transformed proliferating cells. According to PubMed:9840927: low levels in thymus, prostate, brain, skeletal muscle, and kidney. Elevated levels in lung. According to PubMed:9840943 highly expressed in testis, placenta, thymus and brain. In a lesser extent in small intestine and colon

Induction:Activated by papilloma viral oncoproteins E6 and E7 which bind to and inactivate p53 and Rb, respectively
Isoforms & Post-Translational Modification：O96020 has 2 isomers: O96020-1: 46757 Da (predicted); O96020-2: 41465 Da (predicted).
Phosphorylation by CDK2 triggers its release from CDK2 and degradation via the ubiquitin proteasome pathway;Lactylated at Lys-348 (PubMed:36896611). Delactylated by SIRT3 (PubMed:36896611)
Subunit：Interacts with the CDK2 (in vivo) and CDK3 (in vitro) protein kinases to form a serine/threonine kinase holoenzyme complex. The cyclin subunit imparts substrate specificity to the complex
Research Field

Cell Biology
Synonyms
CCNE2; G1/S-specific cyclin-E2
Documentation
User Guide for Antibodies (1077 KB)
References

Cyclin E2 Antibody (YA2594)(PBS only) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Cyclin E2 Antibody (YA2594)(PBS only)
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