Cytochrome C Antibody (YA6421)

Cat. No.: HY-P86729: Data Sheet COA
SDS
User Guide for Antibodies
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Technical Support

Cytochrome C Antibody (YA6421) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome C.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Cytochrome C Antibody (YA6421) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to Cytochrome C.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 12 kDa;

Observed band size: 15 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P99999

Gene ID

54205 [NCBI]

Immunogen

Recombinant human Cytochrome C Protein

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-1:20000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:800
IHC-F IHC-F: Immunohistochemistry-Frozen	1:200-1:800
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:200-1:800

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain|Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases

Subcellular Localization：Mitochondrion intermembrane space

Isoforms & Post-Translational Modification：P99999: 105 amino acids, molecular weight 11749 Da.

Synonyms

CytC; CYC; CYCS; Cytochrome c somatic; HCS; CYC_HUMAN; Cytochrome c; MSA06; THC4.

Documentation

Select Batch:

Data Sheet (231 KB) SDS (252 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)