DAPP1 Antibody (YA7128)
DAPP1 Antibody (YA7128) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DAPP1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
FC, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
FC
FC: Flow Cytometry
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1:400 | 1:10000 |
Product Details
DAPP1 Antibody (YA7128) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DAPP1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 32.2kDa;
SwissProt: SwissProt: Q9UN19
Purified recombinant fragment of human DAPP1 (AA: 127-276) expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DAPP1 may act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K
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Subcellular Localization
Cytoplasm,Membrane
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Expression
Tissue_Specificity: Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells
Induction: Upon B-cell activation -
Isoforms & Post-Translational Modification
Q9UN19 has two isomers: Q9UN19-1: 32194 Da (predicted); Q9UN19-2: 32044 Da (predicted).
Phosphorylated on tyrosine residues -
Subunit
Interacts with PtdIns(3,4,5)P3 and PLCG2
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SwissProt ID
Documentation
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