DLL3 Antibody (YA4534)(PBS only)

Cat. No.: HY-P84837A: Data Sheet User Guide for Antibodies
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DLL3 Antibody (YA4534) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DLL3.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

DLL3 Antibody (YA4534) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DLL3.

Host

Mouse

Molecular Weight

Predicted band size: 65 kDa;

Observed band size: 65 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Rat

SwissProt ID

Q9NYJ7

Gene ID

10683 [NCBI]

Immunogen

Purified recombinant fragment of human DLL3 (AA: EXTRA(27-226)) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm (By similarity)

Subcellular Localization：Membrane; Single-pass type I membrane protein

Isoforms & Post-Translational Modification：Q9NYJ7 has 2 isomers: Q9NYJ7-1: 64618 Da (predicted); Q9NYJ7-2: 61178 Da (predicted).
Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation

Subunit：Can bind and activate Notch-1 or another Notch receptor

Synonyms

SCDO1

Documentation

User Guide for Antibodies (1077 KB)