DLL3 Antibody (YA4534)(PBS only)
(Synonyms: SCDO1)DLL3 Antibody (YA4534) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DLL3.
-
Host:
Mouse
-
Isotype:
IgG2a
-
Application:
WB, IHC-P, ICC/IF, FC, ELISA
-
Reactivity :
Human, Rat
-
Formulation:
Supplied in PBS, pH 7.4.
-
Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
DLL3 Antibody (YA4534) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to DLL3.
-
Host Mouse
-
Species ReactivityHuman, Rat
-
Observed Molecular WeightObserved band size: 65 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 65 kDa
Purified recombinant fragment of human DLL3 (AA: EXTRA(27-226)) expressed in E. Coli.
affinity purified.
Non-conjugated
IgG2a
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS, pH 7.4.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
DLL3 inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm
-
Subcellular Localization
Membrane; Single-pass type I membrane protein
-
Isoforms & Post-Translational Modification
Q9NYJ7 has 2 isomers: Q9NYJ7-1: 64618 Da (predicted); Q9NYJ7-2: 61178 Da (predicted).
Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation -
Subunit
Can bind and activate Notch-1 or another Notch receptor
-
SwissProt ID
-
Synonyms
SCDO1
Documentation