DnaJC7 Antibody (YA9800)
(Synonyms: TPR2, TTC2, DNAJC7, DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2)DnaJC7 Antibody (YA9800) is a Mouse-derived and non-conjugated IgG2 monoclonal antibody, targeting to DnaJC7.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, FC
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Reactivity :
human, mouse, rat
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Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:3000-5000 | 1:200-2000 |
Product Details
DnaJC7 Antibody (YA9800) is a Mouse-derived and non-conjugated IgG2 monoclonal antibody, targeting to DnaJC7.
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Host Mouse
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Species Reactivityhuman, mouse, rat
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Calculated Molecular Weight Predicted band size: 56 kDa
OMIM: 601964
Recombinant protein of human DNAJC7.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DnaJC7 acts as a co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm (By similarity)
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Subcellular Localization
Cytoplasm; Nucleus; Cytoplasm, cytoskeleton
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Isoforms & Post-Translational Modification
DnaJC7 has 2 isoforms, Q99615-1: amino acid length is 494, molecular weight is 56441 Da (predicted); Q99615-2: amino acid length is 438, molecular weight is 50097 Da (predicted).
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Subunit
Associates with complexes containing chaperones HSP70 and HSP90.
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SwissProt ID
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Synonyms
TPR2, TTC2, DNAJC7, DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2
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