DOK2 Antibody (YA8332)(PBS only)
(Synonyms: p56DOK; p56dok-2)DOK2 Antibody (YA8332) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK2.
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Host:
Mouse
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Isotype:
IgG1
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Application:
ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
DOK2 Antibody (YA8332) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DOK2.
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Host Mouse
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 45.2 kDa
Full length human recombinant protein of human DOK2 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DOK2 is a DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK2 may modulate the cellular proliferation induced by IL-4, as well as IL-2 and IL-3. May be involved in modulating Bcr-Abl signaling. Attenuates EGF-stimulated MAP kinase activation
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Expression
Tissue_Specificity: Highly expressed in peripheral blood leukocytes, lymph nodes and spleen. Lower expression in thymus, bone marrow and fetal liver -
Isoforms & Post-Translational Modification
O60496: 412 amino acids, molecular weight 45379 Da.
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Subunit
Interacts with phosphorylated RASGAP and EGFR
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SwissProt ID
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Synonyms
p56DOK; p56dok-2
Documentation