DUPD1 (DUSP27) Antibody (YA8378)(PBS only)
(Synonyms: DUSP27; FMDSP)DUPD1 (DUSP27) Antibody (YA8378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DUPD1 (DUSP27).
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Host:
Mouse
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Isotype:
IgG2b
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Application:
ICC/IF, FC
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Reactivity :
Human, Mouse
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
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Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100-250 | 1:100 |
Product Details
DUPD1 (DUSP27) Antibody (YA8378) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to DUPD1 (DUSP27).
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Host Mouse
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Species ReactivityHuman, Mouse
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Calculated Molecular Weight Predicted band size: 25.2 kDa
Full length human recombinant protein of human DUPD1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG2b
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DUPD1 dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues within the same substrate, with a preference for phosphotyrosine as a substrate. Involved in the modulation of intracellular signaling cascades. In skeletal muscle regulates systemic glucose homeostasis by activating, AMPK, an energy sensor protein kinase. Affects MAP kinase signaling though modulation of the MAPK1/2 cascade in skeletal muscle promoting muscle cell differentiation, development and atrophy[1].
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Subcellular Localization
Cytoplasm,Nucleus
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Isoforms & Post-Translational Modification
Q68J44: 220 amino acids, molecular weight 25336 Da.
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Subunit
Homodimer (PubMed:21543850)
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SwissProt ID
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Synonyms
DUSP27; FMDSP
Documentation
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