Endoglycan Antibody
(Synonyms: P58IPK; PRKRI; DnaJ homolog subfamily C member 3; Endoplasmic reticulum DNA J domain-containing protein 6; ER-resident protein ERdj6; ERdj6; Interferon-induced, double-stranded RNA-activated protein kinase inhibitor; Protein kinase inhibitor of 58 kDa; Protein kinase inhibitor p58)Endoglycan Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Endoglycan.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:50-200 |
Product Details
Endoglycan Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Endoglycan.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 65 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 65 kDa
Synthetic peptide corresponding to the center region of human Endoglycan.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Endoglycan acts as a ligand for vascular selectins. Mediates rapid rolling of leukocytes over vascular surfaces through high affinity divalent cation-dependent interactions with E-, P- and L-selectins
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Subcellular Localization
Membrane
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Expression
Tissue_Specificity: Expressed in T-cells, B-cells and monocytes. Expression is higher on memory and germinal center cells than on naive B-cells (at protein level). Highly expressed in brain. Moderately expressed in pancreas, kidney and lymphoid node. Weakly expressed in liver. Detected in both endothelial cells and CD34+ bone marrow cells. -
Isoforms & Post-Translational Modification
Endoglycan has 2 isoforms, Q9NZ53-1: amino acid length is 605, molecular weight is 65076 Da (predicted); Q9NZ53-2: amino acid length is 529, molecular weight is 56635 Da (predicted).可发生 O-糖基化修饰；含有硫酸软骨素。带有唾液酸化的 O-连接寡糖链Endoglycan 存在 2 个异构体，Q9NZ53-1：氨基酸个数为 605 个，分子量为 65076 Da (预测)；Q9NZ53-2：氨基酸个数为 529 个，分子量为 56635 Da (预测)。O-glycosylated; contains chondroitin sulfate. Displays sialylated O-linked oligosaccharides
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Subunit
Homodimer; disulfide-linked.
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SwissProt ID
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Synonyms
P58IPK; PRKRI; DnaJ homolog subfamily C member 3; Endoplasmic reticulum DNA J domain-containing protein 6; ER-resident protein ERdj6; ERdj6; Interferon-induced, double-stranded RNA-activated protein kinase inhibitor; Protein kinase inhibitor of 58 kDa; Protein kinase inhibitor p58
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