Endothelin Receptor B Antibody (YA9754)
(Synonyms: Endothelin receptor non-selective type, ET-B; ET-BR, Endothelin receptor type B)Endothelin Receptor B Antibody (YA9754) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to Endothelin Receptor B.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, FC, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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FC
FC: Flow Cytometry
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-5000 | 1:200-2000 | 1:100-1000 |
Product Details
Endothelin Receptor B Antibody (YA9754) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to Endothelin Receptor B.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 49.6 kDa;
Recombinant protein of Human Endothelin Receptor B.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) containing 50% glycerol, and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Endothelin Receptor B is a Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Expressed in placental stem villi vessels, but not in cultured placental villi smooth muscle cells. -
Isoforms & Post-Translational Modification
Endothelin Receptor B has 3 isoforms, P24530-1: amino acid length is 442, molecular weight is 49644 Da (predicted); P24530-2: amino acid length is 436, molecular weight is 48710 Da (predicted); P24530-3: amino acid length is 532, molecular weight is 59480 Da (predicted).
Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405. -
SwissProt ID
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Synonyms
Endothelin receptor non-selective type, ET-B; ET-BR, Endothelin receptor type B
Documentation