EphA6 Antibody (YA4834)

Cat. No.: HY-P85142: Data Sheet User Guide for Antibodies
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EphA6 Antibody (YA4834) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EphA6.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

EphA6 Antibody (YA4834) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EphA6.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 116 kDa;

Species Reactivity

Human

SwissProt ID

Q9UF33

Gene ID

285220 [NCBI]

Immunogen

Purified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity)

Subcellular Localization：Membrane; Single-pass type I membrane protein

Expression：
Tissue_specificity:Expressed in brain and testis

Isoforms & Post-Translational Modification：Q9UF33 has 3 isomers: Q9UF33-1: 116379 Da (predicted); Q9UF33-2: 37274 Da (predicted); Q9UF33-3: 44466 Da (predicted).

Subunit：Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity). Interacts (via SAM domain) with ANKS1A (via SAM domain) (By similarity)

Synonyms

EPHA6; EHK2; HEK12; Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12

Documentation

User Guide for Antibodies (1077 KB)