EphA6 Antibody (YA4834)
(Synonyms: EPHA6; EHK2; HEK12; Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12)EphA6 Antibody (YA4834) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EphA6.
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Host:
Mouse
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Application:
WB, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
EphA6 Antibody (YA4834) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to EphA6.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 116 kDa;
Purified recombinant fragment of EphA6 (aa695-795) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EphA6 receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling
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Subcellular Localization
Membrane; Single-pass type I membrane protein
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Expression
Tissue_specificity:Expressed in brain and testis -
Isoforms & Post-Translational Modification
Q9UF33 has 3 isomers: Q9UF33-1: 116379 Da (predicted); Q9UF33-2: 37274 Da (predicted); Q9UF33-3: 44466 Da (predicted).
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Subunit
Heterotetramer upon binding of the ligand. The heterotetramer is composed of an ephrin dimer and a receptor dimer. Oligomerization is probably required to induce biological responses (By similarity). Interacts (via SAM domain) with ANKS1A (via SAM domain) (By similarity)
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SwissProt ID
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Synonyms
EPHA6; EHK2; HEK12; Ephrin type-A receptor 6; EPH homology kinase 2; EHK-2; EPH-like kinase 12; EK12
Documentation
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