FAM40A Antibody (YA8019)

Cat. No.: HY-P88335: Ficha de datos User Guide for Antibodies
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FAM40A Antibody (YA8019) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FAM40A.

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Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

FAM40A Antibody (YA8019) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to FAM40A.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 95.4 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q5VSL9

Immunogen

Full length human recombinant protein of human FAM40A produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:150-500
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Solution

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. Part of the striatin-interacting phosphatase and kinase (STRIPAK) complexes. STRIPAK complexes have critical roles in protein (de)phosphorylation and are regulators of multiple signaling pathways including Hippo, MAPK, nuclear receptor and cytoskeleton remodeling. Different types of STRIPAK complexes are involved in a variety of biological processes such as cell growth, differentiation, apoptosis, metabolism and immune regulation

Subcellular Localization：Cytoplasm

Isoforms & Post-Translational Modification：Q5VSL9 has four isomers: Q5VSL9-1: 95576 Da (predicted); Q5VSL9-2: 85451 Da (predicted); Q5VSL9-3: 49699 Da (predicted); Q5VSL9-4: 23540 Da (predicted).

Subunit：Part of the core of STRIPAK complexes composed of PP2A catalytic and scaffolding subunits, the striatins (PP2A regulatory subunits), the striatin-associated proteins MOB4, STRIP1 and STRIP2, PDCD10 and members of the STE20 kinases, such as STK24 and STK26 (PubMed:18782753, PubMed:33633399)

Synonyms

FAM40A; FAR11A

Documentación

User Guide for Antibodies (1077 KB)