FOXP2 Antibody (YA4865)

製品番号: HY-P85173: データシート User Guide for Antibodies
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FOXP2 Antibody (YA4865) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FOXP2.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

FOXP2 Antibody (YA4865) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to FOXP2.

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 80 kDa;

Species Reactivity

Human

SwissProt ID

O15409

Gene ID

93986 [NCBI]

Immunogen

Purified recombinant fragment of human FoxP2 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:2000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

純度	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language

Subcellular Localization：Nucleus

Expression：
Tissue_specificity:Isomer 1 and isomer 6 are expressed in the human brain, caudate nucleus, and lungs.

Isoforms & Post-Translational Modification：O15409 has 9 isomers: O15409-1: 79919 Da (predicted); O15409-3: Da (predicted); O15409-2: 70104 Da (predicted); O15409-4: 82565 Da (predicted); O15409-5: 18315 Da (predicted); O15409-6: 48764 Da (predicted); O15409-7: 40969 Da (predicted); O15409-8: 9377 Da (predicted); O15409-9: 81840 Da (predicted).

Subunit：Forms homodimers and heterodimers with FOXP1 and FOXP4. Isoform 1 and isoform 3 interact with TBR1 (PubMed:25232744, PubMed:30250039). Interacts with ZMYM2 (PubMed:32891193)

Synonyms

FOXP2; CAGH44; TNRC10; Forkhead box protein P2; CAG repeat protein 44; Trinucleotide repeat-containing gene 10 protein

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/lox-imvi-cell.html [Content Brief]