GATA3 Antibody (YA3897)
(Synonyms: HDR; HDRS)GATA3 Antibody (YA3897) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GATA3.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, IHC-P, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
GATA3 Antibody (YA3897) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GATA3.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 48 kDa
Purified recombinant fragment of human GATA3 (AA: (294-443)) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
GATA3 transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. Positively regulates ASB2 expression. Coordinates macrophage transcriptional activation and UCP2-dependent metabolic reprogramming in response to IL33. Upon tissue injury, acts downstream of IL33 signaling to drive differentiation of inflammation-resolving alternatively activated macrophages
-
Subcellular Localization
Nucleus
-
Expression
Tissue_specificity:T cells and endothelial cells -
Isoforms & Post-Translational Modification
P23771 has 2 isomers: P23771-1: 47916 Da (predicted); P23771-2: 48045 Da (predicted).
-
Subunit
Interacts with TBX21 ('Tyr-530' phosphorylated form)
-
SwissProt ID
-
Synonyms
HDR; HDRS
Documentation
Powered by Bioz
