GBAS Antibody (YA8003)
(Synonyms: NIPSNAP2)GBAS Antibody (YA8003) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GBAS.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:100-250 | 1:100 |
Product Details
GBAS Antibody (YA8003) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GBAS.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 33.6 kDa
Full length human recombinant protein of human GBAS proeduced in E.coli.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GBAS is a Protein involved in mitophagy by facilitating recruitment of the autophagy machinery required for clearance of damaged mitochondria. Accumulates on the mitochondria surface in response to mitochondrial depolarization and acts as a 'eat me' signal by recruiting proteins involved in selective autophagy, such as autophagy receptors (CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY) and ATG8 family proteins (MAP1LC3A, MAP1LC3B, MAP1LC3C, GABARAP, GABARAPL1 and GABARAPL2)[1].
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Subcellular Localization
Mitochondrion matrix
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Expression
Tissue_Specificity: Widely expressed (PubMed:9615231). Most abundant in heart and skeletal muscle (PubMed:9615231) -
Isoforms & Post-Translational Modification
O75323 has two isomers: O75323-1: 33743 Da (predicted); O75323-2: 29053 Da (predicted).
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Subunit
Interacts with CALCOCO2/NDP52, NBR1, SQSTM1/p62, TAX1BP1 and WDFY3/ALFY (PubMed:30982665)
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SwissProt ID
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Synonyms
NIPSNAP2
Documentation
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