GIRK2 Antibody (YA6888)

Cat. No.: HY-P87200: Data Sheet COA
SDS
User Guide for Antibodies
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GIRK2 Antibody (YA6888) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GIRK2.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
Documentation

Description

GIRK2 Antibody (YA6888) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GIRK2.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size：48 kDa;

Observed band size: 35/48 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat Predicted Reactivity: Cynomolgus monkey,Pig

Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.

SwissProt ID

P48051

Immunogen

Recombinant protein.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:1000
IP IP: Immunoprecipitation	1-2μg/sample
IHC-F IHC-F: Immunohistochemistry-Frozen	1:500

Purity	affinity purified.	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from MG-63 (lane 1(20μg, negative)) 、Mouse brain (lane 2(20μg)) and Rat brain (lane 3(20μg)) using GIRK2 Antibody (HY-P87200) . Proteins were transferred to a PVDF membrane and blocked with 5% nonfat dry milk in TBST for 1.5 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Hsp90, 1/10000) was used in 5% nonfat dry milk in TBST at 4℃ overnight. Goat Anti-Rabbit IgG-HRP Secondary Antibody (1/10,000) was used for 1 hour at room temperature.

Background

Function：Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This potassium channel may be involved in the regulation of insulin secretion by glucose and/or neurotransmitters acting through G-protein-coupled receptors

Subcellular Localization：Membrane

Expression：
Tissue_Specificity: Most abundant in cerebellum, and to a lesser degree in islets and exocrine pancreas

Isoforms & Post-Translational Modification：P48051: 423 amino acids, molecular weight 48451 Da.

Subunit：Associates with KCNJ3/GIRK1 or KCNJ5/GRIK4 to form a G-protein-activated heteromultimer pore-forming unit

Synonyms

inwardly rectifying subfamily J member 6 antibody

Documentation

Select Batch:

Data Sheet (231 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)