GLRB Antibody (YA4044)(PBS only)

Cat. No.: HY-P84347A: Data Sheet User Guide for Antibodies
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GLRB Antibody (YA4044) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GLRB.

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사이즈		재고
50 μL		견적 받기
100 μL		견적 받기

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

GLRB Antibody (YA4044) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to GLRB.

Host

Mouse

분자량

Predicted band size: 54 kDa;

Observed band size: 54 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P48167

Gene ID

2743 [NCBI]

Immunogen

Purified recombinant fragment of human GLRB (AA: extra 23-160) expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Purity	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Subunit of heteromeric glycine-gated chloride channels (PubMed:11929858, PubMed:15302677, PubMed:16144831, PubMed:22715885, PubMed:23238346, PubMed:25445488, PubMed:34473954, PubMed:8717357). Plays an important role in the down-regulation of neuronal excitability (PubMed:11929858, PubMed:23238346). Contributes to the generation of inhibitory postsynaptic currents (PubMed:25445488)

Subcellular Localization：Postsynaptic cell membrane; Multi-pass membrane protein; Synapse; Cell projection, dendrite; Cell membrane; Multi-pass membrane protein; Cytoplasm

Isoforms & Post-Translational Modification：P48167 has 2 isomers: P48167-1: 56122 Da (predicted); P48167-2: 34944 Da (predicted).

Subunit：Forms heteropentamers with glycin receptor alpha subunits. Heteropentamers with GLRA1 can be composed of two GLRA1 and three GLRB subunits, or three GLRA1 and two GLRB subunits, or four GLRA1 subunits and one GLRB subunit (PubMed:11929858, PubMed:14551753, PubMed:22715885, PubMed:22973015, PubMed:23238346, PubMed:25445488, PubMed:8717357, PubMed:35526563, PubMed:37821459). Forms heteropentamers with GLRA2 (PubMed:15302677, PubMed:16144831, PubMed:25445488, PubMed:34473954). Functional GLRB-GLRA2 heteropentamers contain four GLRA2 subunits and one GLRB subunit, although alternative subunit composition cannot be excluded (PubMed:34473954). Forms a heteropentamer with GLRA3 (PubMed:25445488). Interacts with GPHN (PubMed:12684523, PubMed:26613940)

Synonyms

HKPX2

각종 서류

User Guide for Antibodies (1077 KB)