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GPR19 Antibody (YA7126)(PBS only)

(Synonyms: Probable G-protein coupled receptor 19, GPR-NGA, GPR19)

GPR19 Antibody (YA7126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GPR19.

For research use only. We do not sell to patients.
  • Host:

    Mouse

  • Isotype:

    IgG2a

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    Supplied in PBS, pH 7.4.

  • Conjugation:
    Non-conjugated
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:200-1:400 1:10000

Product Details

Description

GPR19 Antibody (YA7126) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to GPR19.

  • Host Mouse
  • Species Reactivity
    Human
  • Calculated Molecular Weight Predicted band size: 47.6kDa;
Immunogen

Purified recombinant fragment of human GPR19 expressed in E. Coli.

Purification

affinity purified.

Conjugation

Non-conjugated

Isotype

IgG2a

Product Properties

  • Appearance

    Solution

  • Formulation

    Supplied in PBS, pH 7.4.

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    GPR19 is a G-protein coupled receptor that plays a role in the regulation of circadian rhythms and energy metabolism. Participates in maintaining proper circadian gene expression in the suprachiasmatic nucleus (SCN), the locus of the master circadian clock in the brain. May function as a coordinator of aging-associated metabolic dysfunction, stress response, DNA integrity management, and eventual senescence. Upon binding to adropin, modulates mitochondrial energy metabolism via the p44/42-PDK4 signaling pathway, influencing pyruvate dehydrogenase activity[1].

  • Subcellular Localization

    Cell membrane

  • Expression


    Tissue_Specificity: Abundant expression in the brain

  • Isoforms & Post-Translational Modification

    Q15760: 415 amino acids, molecular weight 47687 Da.

  • SwissProt ID

    Q15760

  • Synonyms

    Probable G-protein coupled receptor 19, GPR-NGA, GPR19

GPR19 Antibody (YA7126)(PBS only) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • GPR19 Antibody (YA7126)(PBS only) Product Image