GRIPAP1 (GRASP1) Antibody (YA8161)
(Synonyms: GRASP-1)GRIPAP1 (GRASP1) Antibody (YA8161) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIPAP1 (GRASP1).
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|
| Dilution Ratio | 1:50-250 | 1:100-250 | 1:100 |
Product Details
GRIPAP1 (GRASP1) Antibody (YA8161) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIPAP1 (GRASP1).
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 96.0 kDa
Full length human recombinant protein of human GRIPAP1 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
GRIPAP1 regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity|Functions as a scaffold protein to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity
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Subcellular Localization
Early endosome membrane,Recycling endosome membrane,Cell projection, axon,Cell projection, dendrite,Synapse
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Isoforms & Post-Translational Modification
Q4V328 has three isomers: Q4V328-1: 96006 Da (predicted); Q4V328-2: 71894 Da (predicted); Q4V328-4: 92754 Da (predicted).
Proteolytically cleaved by caspase-3 -
Subunit
Interacts with GRIP1, GRIP2 and AMPA receptors (By similarity)
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SwissProt ID
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Synonyms
GRASP-1
Documentation
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