GRIPAP1 (GRASP1) Antibody (YA8161)

製品番号: HY-P88477: データシート User Guide for Antibodies
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GRIPAP1 (GRASP1) Antibody (YA8161) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIPAP1 (GRASP1).

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

GRIPAP1 (GRASP1) Antibody (YA8161) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to GRIPAP1 (GRASP1).

Host

Mouse

Clonality

Monoclonal

分子量

Predicted band size: 96.0 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q4V328

Immunogen

Full length human recombinant protein of human GRIPAP1 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-250
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	純度	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Regulates the endosomal recycling back to the neuronal plasma membrane, possibly by connecting early and late recycling endosomal domains and promoting segregation of recycling endosomes from early endosomal membranes. Involved in the localization of recycling endosomes to dendritic spines, thereby playing a role in the maintenance of dendritic spine morphology. Required for the activity-induced AMPA receptor recycling to dendrite membranes and for long-term potentiation and synaptic plasticity (By similarity)|Functions as a scaffold protein to facilitate MAP3K1/MEKK1-mediated activation of the JNK1 kinase by phosphorylation, possibly by bringing MAP3K1/MEKK1 and JNK1 in close proximity

Subcellular Localization：Early endosome membrane,Recycling endosome membrane,Cell projection, axon,Cell projection, dendrite,Synapse

Isoforms & Post-Translational Modification：Q4V328 has three isomers: Q4V328-1: 96006 Da (predicted); Q4V328-2: 71894 Da (predicted); Q4V328-4: 92754 Da (predicted).
Proteolytically cleaved by caspase-3

Subunit：Interacts with GRIP1, GRIP2 and AMPA receptors (By similarity)

Synonyms

GRASP-1

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/huvec-cell.html [Content Brief]