GTPBP4 Antibody (YA2189)
(Synonyms: CRFG; GTP binding protein 4; Gtpbp4; NGB; NOG1)GTPBP4 Antibody (YA2189) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GTPBP4.
-
Host:
Rabbit
-
Isotype:
IgG
-
Application:
WB, IHC-P, IP, FC
-
Reactivity :
Human
-
Formulation:
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
IHC-P
IHC-P: Immunohistochemistry-Paraffin
|
IP
IP: Immunoprecipitation
|
FC
FC: Flow Cytometry
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:50 | 1:50-1:100 |
Product Details
GTPBP4 Antibody (YA2189) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to GTPBP4.
-
Host Rabbit
-
Clonality Recombinant,Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 80 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 74 kDa
A synthesized peptide derived from human GTPBP4 aa50-100/634.
Endogenous
Affinity Chromatography
Non-conjugated
Unmodified
IgG
Product Properties
-
Appearance
Solution
-
Formulation
Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
GTPBP4 is involved in the biogenesis of the 60S ribosomal subunit. Acts as a TP53 repressor, preventing TP53 stabilization and cell cycle arrest[1][2].
-
Subcellular Localization
Nucleus, nucleolus
-
Isoforms & Post-Translational Modification
Q9BZE4 has 3 isomers: Q9BZE4-1: 73964 Da (predicted); Q9BZE4-2: 68273 Da (predicted); Q9BZE4-3: 60051 Da (predicted).
-
Subunit
Associates with pre-60S ribosomal particles (PubMed:32669547). Interacts with MINAS-60 (product of an alternative open reading frame of RBM10) (PubMed:35393574)
-
SwissProt ID
-
Synonyms
CRFG; GTP binding protein 4; Gtpbp4; NGB; NOG1
-
Research Field
Signal Transduction
Documentation
References
[1]. Liang X, et al. Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun. 2020 Jul 15;11(1):3542. [Content Brief]
[2]. Lunardi A, et al. A genome-scale protein interaction profile of Drosophila p53 uncovers additional nodes of the human p53 network. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6322-7. [Content Brief]
Powered by Bioz
