HMGA1 Antibody (YA7650)
(Synonyms: HMGIY, HMGA1, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein R, High mobility group protein A1)
Based on 1 Customer Validation
HMGA1 Antibody (YA7650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGA1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IP, FC
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Reactivity :
Human, Mouse
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:1000-1:5000 | 1:200-1:500 | 1:200-1:500 | 1:20-1:50 |
Product Details
HMGA1 Antibody (YA7650) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HMGA1.
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Host Rabbit
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Clonality Recombinant
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Species ReactivityHuman, Mouse Predicted Reactivity: Rat
Note: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 17 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 12 kDa
A synthesized peptide derived from human HMGA1
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
HMGA1 is a HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3'-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions
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Subcellular Localization
Nucleus,Chromosome
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Isoforms & Post-Translational Modification
P17096 has three isomers: P17096-1: 11676 Da (predicted); P17096-2: 10679 Da (predicted); P17096-3: 19694 Da (predicted).
Constitutively phosphorylated on two or three sites丨HMG-Y is not methylated丨Methylation at Arg-58 is mutually exclusive with methylation at Arg-60 -
Subunit
Interacts with HIPK2 (By similarity)
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SwissProt ID
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Synonyms
HMGIY, HMGA1, High mobility group protein HMG-I/HMG-Y, HMG-I(Y), High mobility group AT-hook protein 1, High mobility group protein R, High mobility group protein A1
Documentation
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