Human CD200R1 Antibody (YA6603)
(Synonyms: CD 200R antibody; CD200 cell surface glycoprotein receptor antibody; CD200 receptor 1 antibody; Cd200r1 antibody; Cell surface glycoprotein CD200 receptor 1 antibody; Cell surface glycoprotein OX2 receptor 1 antibody; Cell surface glycoprotein OX2 receptor antibody; cell surface glycoprotein receptor CD200 antibody; CRTR 2 antibody; CRTR2 antibody; CD 200R antibody; CD200 cell surface glycoprotein receptor antibody; CD200 receptor 1 antibody; Cd200r1 antibody; Cell surface glycoprotein CD200 receptor 1 antibody; Cell surface glycoprotein OX2 receptor 1 antibody; Cell surface glycoprotein OX2 receptor antibody; cell surface glycoprotein receptor CD200 antibody; CRTR 2 antibody; CRTR2 antibody; HCRTR2 antibody; MO2R1_HUMAN antibody; MOX2 receptor antibody; MOX2R antibody; OX2R antibody; )Human CD200R1 Antibody (YA6603) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human CD200R1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|
| Dilution Ratio | 1:100 | 1:1000 |
Product Details
Human CD200R1 Antibody (YA6603) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human CD200R1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 39 kDa
Recombinant protein within human CD200R1 aa 29-265 / 348.
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Human CD200R1 is an Inhibitory receptor for the CD200/OX2 cell surface glycoprotein. Limits inflammation by inhibiting the expression of pro-inflammatory molecules including TNF-alpha, interferons, and inducible nitric oxide synthase (iNOS) in response to selected stimuli. Also binds to HHV-8 K14 viral CD200 homolog with identical affinity and kinetics as the host CD200
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Subcellular Localization
Cell membrane,Cell membrane,Secreted,Secreted
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Expression
Tissue_Specificity: Expressed in granulocytes, monocytes, most T-cells, neutrophils, basophils and a subset of NK, NKT and B-cells (at protein level). Expressed in bone marrow, lymph nodes, spleen, lung, liver, spinal cord, kidney. Expressed in monocyte-derived dendritic and mast cells -
Isoforms & Post-Translational Modification
Q8TD46 has four isomers: Q8TD46-4: 39041 Da (predicted); Q8TD46-1: 36605 Da (predicted); Q8TD46-2: 21291 Da (predicted); Q8TD46-3: 18855 Da (predicted).
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Subunit
CD200 and CD200R1 interact via their respective N-terminal Ig-like domains (By similarity)
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SwissProt ID
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Synonyms
CD 200R antibody; CD200 cell surface glycoprotein receptor antibody; CD200 receptor 1 antibody; Cd200r1 antibody; Cell surface glycoprotein CD200 receptor 1 antibody; Cell surface glycoprotein OX2 receptor 1 antibody; Cell surface glycoprotein OX2 receptor antibody; cell surface glycoprotein receptor CD200 antibody; CRTR 2 antibody; CRTR2 antibody; CD 200R antibody; CD200 cell surface glycoprotein receptor antibody; CD200 receptor 1 antibody; Cd200r1 antibody; Cell surface glycoprotein CD200 receptor 1 antibody; Cell surface glycoprotein OX2 receptor 1 antibody; Cell surface glycoprotein OX2 receptor antibody; cell surface glycoprotein receptor CD200 antibody; CRTR 2 antibody; CRTR2 antibody; HCRTR2 antibody; MO2R1_HUMAN antibody; MOX2 receptor antibody; MOX2R antibody; OX2R antibody;
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