Human kappa Light Chain Antibody (YA1996)

Cat. No.: HY-P82251: Data Sheet COA
SDS
User Guide for Antibodies
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Human kappa Light Chain Antibody (YA1996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human kappa Light Chain.

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사이즈	재고	수량
20 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

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Human kappa Light Chain Antibody (YA1996) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
제품 설명

제품 설명

Human kappa Light Chain Antibody (YA1996) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Human kappa Light Chain.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 12 kDa;

Observed band size: 26 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

P01834

Gene ID

3514 [NCBI]

Immunogen

A synthesized peptide derived from human Human Kappa Chain IgM from human serum.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Background

Function：Constant region of immunoglobulin light chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens (PubMed:20176268, PubMed:22158414). The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen (PubMed:17576170, PubMed:20176268)

Subcellular Localization：Secreted; Cell membrane

Subunit：Immunoglobulins are composed of two identical heavy chains and two identical light chains; disulfide-linked

Database

Entrez Gene: 3514 Human

SwissProt: P01834 Human

OMIM: 614102 Human

Research Field

Immunology

Synonyms

HCAK1; Ig kappa chain C region; IGKC; IMMUNOGLOBULIN InV; Km

각종 서류

Select Batch:

Data Sheet (234 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

Human kappa Light Chain Antibody (YA1996) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Human kappa Light Chain Antibody (YA1996)

Human kappa Light Chain Antibody (YA1996) Featured Recommendations:

Product Detail

Background

제품 설명

Human kappa Light Chain Antibody (YA1996) Related Classifications

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SAFETY DATA SHEET (SDS)

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