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IL-2 Receptor alpha Antibody (YA1457)

(Synonyms: IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25)
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IL-2 Receptor alpha Antibody (YA1457) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    FC, ELISA

  • Reactivity :

    Human

  • Formulation:

    1.Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
    2.Supplied in PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization.
    Please refer to the lot-specific COA for specific buffer information.

  • Conjugation:
    Non-conjugated
  • IL-2 Receptor alpha Antibody (YA1457) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Related Products:
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Use of MCE Products

Applications

Application
FC Info
FC: Flow Cytometry
ELISA Info
ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio 1:50-1:100 1:10000

Product Details

Description

IL-2 Receptor alpha Antibody (YA1457) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IL-2 Receptor alpha.

  • Host Rabbit
  • Clonality Recombinant,Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 60 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 30.8 kDa
Species Reactivity Database

Entrez Gene: 3559 Human

SwissProt: P01589 Human

Immunogen

Recombinant human IL2RA protein

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

RRID

AB_3103819

Product Properties

  • Appearance

    Solution

  • Formulation

    1.Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
    2.Supplied in PBS, pH 7.4. Normally 5% - 8% trehalose is added as protectants before lyophilization.
    Please refer to the lot-specific COA for specific buffer information.

  • Concentration

    Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    IL-2 Receptor alpha is an interleukin-2 receptor. IL-2 Receptor alpha participates in the regulation of immune tolerance by controlling the activity of regulatory T cells (TREGs). TREGs inhibit the activation and proliferation of autoreactive T cells.

  • Subcellular Localization

    Membrane; Single-pass type I membrane protein

  • Subunit

    Non-covalent dimer of an alpha and a beta subunit. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit

  • SwissProt ID

    P01589

  • Gene ID
    3559 [NCBI]
  • Synonyms

    IL2RA; Interleukin-2 receptor subunit alpha; IL-2 receptor subunit alpha; IL-2-RA; IL-2R subunit alpha; IL2-RA; TAC antigen; p55; CD25

  • Research Field

    Immunology

IL-2 Receptor alpha Antibody (YA1457) Related Classifications

MOQ
Minimum order quantity
100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
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  • IL-2 Receptor alpha Antibody (YA1457) Product Image