IL34 Antibody (YA4346)
(Synonyms: IL-34; C16orf77; MGC34647; IL34)IL34 Antibody (YA4346) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL34.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, ICC/IF, FC, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide.
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:200-1:1000 | 1:200-1:400 | 1:10000 |
Product Details
IL34 Antibody (YA4346) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL34.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 27 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 27 kDa
Purified recombinant fragment of human IL34 aa 21-242.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS with 0.05% sodium azide.
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
IL34 is a Cytokine that promotes the proliferation, survival and differentiation of monocytes and macrophages. Promotes the release of pro-inflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, and in the regulation of bone resorption. Signaling via CSF1R and its downstream effectors stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1
-
Subcellular Localization
Secreted
-
Expression
Tissue_specificity:This protein was detected (protein level) in the sinusoidal epithelial cells of the red pulp of the spleen. It is primarily expressed in the spleen. Furthermore, it has been detected in a variety of other tissues, including the heart, brain, lungs, liver, kidneys, thymus, testes, ovaries, small intestine, prostate, and colon. -
Subunit
Homodimer. Interacts with CSF1R
-
SwissProt ID
-
Synonyms
IL-34; C16orf77; MGC34647; IL34
Documentation
-
Data Sheet (234 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
User Guide for Antibodies (1077 KB)
Powered by Bioz
