IRF6 Antibody (YA2662)

Cat. No.: HY-P82917: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
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IRF6 Antibody (YA2662) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IRF6.

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10 μL	해외재고보유	Estimated Time of Arrival: December 31
50 μL	해외재고보유	Estimated Time of Arrival: December 31
100 μL	해외재고보유	Estimated Time of Arrival: December 31
250 μL	견적 받기

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IRF6 Antibody (YA2662) Featured Recommendations:

1 Publications Citing Use of MCE IRF6 Antibody (YA2662)

•JCI Insight. 2025 Nov 10;10(21):e189420. [Abstract]

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Verification Image
Background
제품 설명

제품 설명

IRF6 Antibody (YA2662) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to IRF6.

Host

Rabbit

Clonality

Recombinant,Monoclonal

분자량

Predicted band size: 53 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

O14896

Gene ID

3664 [NCBI]

Immunogen

A synthesized peptide derived from human IRF6 aa404-467.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	Purity	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 10mM PBS, pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

선적

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from Jurkat(lane 2(20ug) and K562(lane 3(20ug) using IRF6 Antibody (HY-P82917) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

Function：Probable DNA-binding transcriptional activator. Key determinant of the keratinocyte proliferation-differentiation switch involved in appropriate epidermal development (By similarity). Plays a role in regulating mammary epithelial cell proliferation (By similarity). May regulate WDR65 transcription (By similarity)

Subcellular Localization：Nucleus; Cytoplasm

Expression：
Tissue_specificity:Expressed in normal mammary epithelial cells. Expression is reduced or absent in breast carcinomas

Isoforms & Post-Translational Modification：O14896 has 2 isomers: O14896-1: 53130 Da (predicted); O14896-2: 41930 Da (predicted).
Phosphorylated. Phosphorylation status depends on the cell cycle and is a signal for ubiquitination and proteasome-mediated degradation

Subunit：Interacts with SERPINB5

RRID

AB_3105009

Database

Entrez Gene: 3664 Human ;

SwissProt: O14896 Human ;

OMIM: 119300 Human

Research Field

Immunology

Synonyms

anti-Interferon regulatory factor 6; anti-IRF 6; anti-LPS; anti-OFC 6; anti-PIT; anti-PPS; anti-PPS1; anti-VWS; anti-VWS1; Interferon regulatory factor 6 antibody; IRF 6 antibody; LPS antibody; OFC 6 antibody; PIT antibody; PPS antibody; PPS1 antibody; VWS antibody; VWS1 antibody;

각종 서류

Select Batch:

Data Sheet (232 KB) SDS (252 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

IRF6 Antibody (YA2662) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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IRF6 Antibody (YA2662)

IRF6 Antibody (YA2662) Featured Recommendations:

1 Publications Citing Use of MCE IRF6 Antibody (YA2662)

Product Detail

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Background

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IRF6 Antibody (YA2662) Related Classifications

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