KIAA1609 Antibody (YA8489)

Cat. No.: HY-P88805: Ficha de datos User Guide for Antibodies
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KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.

Para uso exclusivo en investigación. No vendemos a pacientes.

Tamaño		Stock
50 μL		Obtener un presupuesto
100 μL		Obtener un presupuesto

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Descripciòn

Descripciòn

KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.

Host

Mouse

Clonality

Monoclonal

Peso molecular

Predicted band size: 50.8 kDa

Species Reactivity

Human

SwissProt ID

Q6P9B6

Immunogen

Full length human recombinant protein of human KIAA1609 produced in HEK293T cell.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:2000-3000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-250
FC FC: Flow Cytometry	1:100

Sensitivity	Endogenous	Pureza	Affinity purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Envío

Shipping with blue ice.

Background

Function：Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration (PubMed:29750193). Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome (PubMed:29750193)

Subcellular Localization：Membrane,Cytoplasm,Lysosome

Expression：Induction: Addition of nutrients and insulin induces its expression (at protein level)

Isoforms & Post-Translational Modification：Q6P9B6: 456 amino acids, molecular weight 50994 Da.

Subunit：Interacts (via C-terminal domain) with MTOR and MLST8; the interaction with MTOR increases upon nutrient stimulation

Synonyms

KIAA1609

Documentación

User Guide for Antibodies (1077 KB)