KIAA1609 Antibody (YA8489)
(Synonyms: KIAA1609)KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.
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Host:
Mouse
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Isotype:
IgG2a
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Application:
WB, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Conjugation:
Non-conjugated
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Applications
| Application |
WB
WB: Western Blot
|
ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
|
|---|---|---|---|
| Dilution Ratio | 1:2000-3000 | 1:100-250 | 1:100 |
Product Details
KIAA1609 Antibody (YA8489) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to KIAA1609.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 50.8 kDa
Full length human recombinant protein of human KIAA1609 produced in HEK293T cell.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG2a
Product Properties
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Appearance
Liquid
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Formulation
Spplied in PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
KIAA1609 activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome[1].
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Subcellular Localization
Membrane,Cytoplasm,Lysosome
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Expression
Induction: Addition of nutrients and insulin induces its expression (at protein level)
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Isoforms & Post-Translational Modification
Q6P9B6: 456 amino acids, molecular weight 50994 Da.
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Subunit
Interacts (via C-terminal domain) with MTOR and MLST8; the interaction with MTOR increases upon nutrient stimulation
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SwissProt ID
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Synonyms
KIAA1609
Documentation
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