KIF22 Antibody (YA4273)(PBS only)

Cat. No.: HY-P84576A: Fiche technique User Guide for Antibodies
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KIF22 Antibody (YA4273) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KIF22.

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Size		Stock
50 μL		Obtenir un devis
100 μL		Obtenir un devis

* Veuillez sélectionner la quantité avant d'ajouter des articles.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Description
Références

Description

KIF22 Antibody (YA4273) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to KIF22.

Host

Mouse

Masse moléculaire

Predicted band size: 73 kDa;

Observed band size: 73 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q14807

Gene ID

3835 [NCBI]

Immunogen

Purified recombinant fragment of human KID aa 225-419.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
FC FC: Flow Cytometry	1:200-1:400
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Pureté	affinity purified.	Conjugation	Non-conjugated
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Livraison

Shipping with blue ice.

Background

Function：Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80-depleted cells (PubMed:25743205)

Subcellular Localization：Nucleus; Cytoplasm, cytoskeleton

Expression：
Tissue_specificity:It is expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes.

Isoforms & Post-Translational Modification：Q14807 has 2 isomers: Q14807-1: 73262 Da (predicted); Q14807-2: 66307 Da (predicted).
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation

Subunit：Interacts with FAM83D (PubMed:18485706). Interacts with SIAH1 (PubMed:11146551)

Synonyms

KIF22; KID; OBP; KNSL4; OBP-1; OBP-2; A-328A3.2

Documentation

User Guide for Antibodies (1077 KB)

Références

[1]. /biology-dictionary/d-502mg-cell.html