KLF10 Antibody (YA2349)

Cat. No.: HY-P82604: Data Sheet COA
SDS
User Guide for Antibodies
FAQs
Technical Support

KLF10 Antibody (YA2349) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KLF10.

For research use only. We do not sell to patients.

Size	Stock	Quantity
Free Sample	Apply now
10 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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KLF10 Antibody (YA2349) Featured Recommendations:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
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Background
Documentation

Description

KLF10 Antibody (YA2349) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to KLF10.

Host

Rabbit

Clonality

Recombinant,Monoclonal

Molecular Weight

Predicted band size: 53 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q13118

Gene ID

7071 [NCBI]

Immunogen

A synthesized peptide derived from human KLF10 aa40-100/480.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000

Sensitivity	Endogenous	Purity	Affinity Purified
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Verification Image

Western blot analysis of extracts from Jurkat(lane 2(20ug) , MCF-7(lane 3(20ug) and HEK293(lane 4(20ug) using KLF10 Antibody (HY-P82604) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P83730, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

Background

Function：Transcriptional repressor which binds to the consensus sequence 5'-GGTGTG-3'. Plays a role in the regulation of the circadian clock; binds to the GC box sequence in the promoter of the core clock component ARTNL/BMAL1 and represses its transcriptional activity. Regulates the circadian expression of genes involved in lipogenesis, gluconeogenesis, and glycolysis in the liver. Represses the expression of PCK2, a rate-limiting step enzyme of gluconeogenesis (By similarity). May play a role in the cell cycle regulation

Subcellular Localization：Nucleus

Expression：
Induction:By TGFB1 and BMP2

Isoforms & Post-Translational Modification：Q13118 has 4 isomers: Q13118-1: 52555 Da (predicted); Q13118-2: 51424 Da (predicted); Q13118-3: 10600 Da (predicted); Q13118-4: 13702 Da (predicted).
Ubiquitinated; mediated by SIAH1 and leading to its subsequent proteasomal degradation

RRID

AB_3104705

Database

Entrez Gene: 7071 Human ; 21847 Mouse ; 81813 Rat

SwissProt: Q13118 Human ; O89091 Mouse ; O08876 Rat

OMIM: 601878 Human

Research Field

Epigenetics and Nuclear Signaling

Synonyms

EGR alpha; EGRA; Egral; EGRalpha; Gdnfif; KLF10; mGIF; TIEG; TIEG1

Documentation

Select Batch:

Data Sheet (232 KB) SDS (251 KB)

COA (206 KB)

User Guide for Antibodies (1077 KB)

KLF10 Antibody (YA2349) Related Classifications

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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KLF10 Antibody (YA2349)

KLF10 Antibody (YA2349) Featured Recommendations:

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Background

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KLF10 Antibody (YA2349) Related Classifications

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