LMCD1 Antibody (YA7960)(PBS only)
(Synonyms: dyxin; LIM and cysteine-rich domains 1)LMCD1 Antibody (YA7960) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LMCD1.
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Host:
Mouse
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Isotype:
IgG1
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:2000 | 1:150-500 | 1:100-250 | 1:100 |
Product Details
LMCD1 Antibody (YA7960) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to LMCD1.
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Host Mouse
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 40.7 kDa
Full length human recombinant protein of human LMCD1 produced in HEK293T cell.
Affinity purified
Non-conjugated
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
LMCD1 transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter. Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway
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Subcellular Localization
Cytoplasm,Nucleus
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Expression
Tissue_Specificity: Expressed in the heart (at protein level). Expressed in many tissues with highest abundance in skeletal muscle -
Isoforms & Post-Translational Modification
Q9NZU5 has two isomers: Q9NZU5-1: 40833 Da (predicted); Q9NZU5-2: 32882 Da (predicted).
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Subunit
Interacts with GATA1 and GATA4 (By similarity)
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SwissProt ID
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Synonyms
dyxin; LIM and cysteine-rich domains 1
Documentation
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