Mint3 Antibody (YA3242)

製品番号: HY-P83497: データシート User Guide for Antibodies
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Technical Support

Mint3 Antibody (YA3242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mint3.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

容量	価格（税別）	在庫状況	数量
20 μL	$146	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
50 μL	$222	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
100 μL	$360	Get quote 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks	Estimated Time of Arrival: December 31
250 μL		お問い合わせ

Synthetic products have potential research and development risk.

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* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明

製品説明

Mint3 Antibody (YA3242) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mint3.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 53 kDa;

Observed band size: 53 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse

SwissProt ID

Q8IUF8

Gene ID

84864 [NCBI]

Immunogen

A synthesized peptide derived from human MINA53 aa416-465.

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:50-1:200

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase. Is involved in the demethylation of trimethylated 'Lys-9' on histone H3 (H3K9me3), leading to an increase in ribosomal RNA expression. Also catalyzes the hydroxylation of 60S ribosomal protein L27a on 'His-39'. May play an important role in cell growth and survival. May be involved in ribosome biogenesis, most likely during the assembly process of pre-ribosomal particles

Subcellular Localization：Nucleus; Nucleus, nucleolus

Expression：
Tissue_specificity:Expressed in liver, skeletal muscle, heart, pancreas, and placenta. Not detected in brain, lung or kidney. Expressed in several lung cancer tissues, but is barely detected in the adjacent non-cancerous tissues. Also highly expressed in several esophageal squamous cell carcinoma (ESCC) , and colon cancer tissues, and in various cancer cell lines

Induction:Up-regulated in response to MYC, in alveolar macrophages from coal miners and in silica particle-treated A549 lung cancer cells

Isoforms & Post-Translational Modification：Q8IUF8 has 4 isomers: Q8IUF8-1: 52800 Da (predicted); Q8IUF8-2: 31818 Da (predicted); Q8IUF8-3: 23909 Da (predicted); Q8IUF8-4: 52672 Da (predicted).

Database

Entrez Gene: 84864 Human ; 57267 Mouse ;

SwissProt: Q8IUF8 Human ; O88888 Mouse ;

OMIM: 612049 Human

Research Field

Synonyms

Histone lysine demethylase MINA; MDIG; MINA; NO52; ROX

ドキュメンテーション

User Guide for Antibodies (1077 KB)