Mitofilin Antibody (YA3231)(PBS only)
(Synonyms: HMP; P87; P89; PIG4; Mic60; PIG52; MINOS2; P87/89)Mitofilin Antibody (YA3231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mitofilin.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, FC
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Reactivity :
Human
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Formulation:
Supplied in PBS, pH 7.4.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
FC
FC: Flow Cytometry
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|---|---|---|---|---|
| Dilution Ratio | 1:1000-1:5000 | 1:100-1:200 | 1:100-1:500 | 1:10-1:100 |
Product Details
Mitofilin Antibody (YA3231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mitofilin.
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Host Rabbit
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 84 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 84 kDa
A synthetic peptide of human Mitofilin
Affinity Purified
Non-conjugated
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS, pH 7.4.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Mitofilin component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology[1][2][3][4].
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Subcellular Localization
Mitochondrion inner membrane; Single-pass membrane protein; Mitochondrion
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Isoforms & Post-Translational Modification
Q16891 has 4 isomers: Q16891-1: 83678 Da (predicted); Q16891-2: 82625 Da (predicted); Q16891-3: 80027 Da (predicted); Q16891-4: 83549 Da (predicted).
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Subunit
Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MICOS10/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and MICOS13/MIC13 (PubMed:25764979, PubMed:25781180, PubMed:32567732).
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SwissProt ID
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Synonyms
HMP; P87; P89; PIG4; Mic60; PIG52; MINOS2; P87/89
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Research Field
Signal Transduction
Documentation