Mitofilin Antibody (YA3231)(PBS only)

Cat. No.: HY-P83486A: Data Sheet User Guide for Antibodies
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Mitofilin Antibody (YA3231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mitofilin.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

Mitofilin Antibody (YA3231) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Mitofilin.

Host

Rabbit

Molecular Weight

Predicted band size: 84 kDa;

Observed band size: 84 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q16891

Gene ID

10989 [NCBI]

Immunogen

A synthetic peptide of human Mitofilin

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:1000-1:5000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-1:200
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:100-1:500
FC FC: Flow Cytometry	1:10-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824). Plays an important role in the maintenance of the MICOS complex stability and the mitochondrial cristae morphology (PubMed:22114354, PubMed:25781180, PubMed:32567732, PubMed:33130824)

Subcellular Localization：Mitochondrion inner membrane; Single-pass membrane protein; Mitochondrion

Isoforms & Post-Translational Modification：Q16891 has 4 isomers: Q16891-1: 83678 Da (predicted); Q16891-2: 82625 Da (predicted); Q16891-3: 80027 Da (predicted); Q16891-4: 83549 Da (predicted).

Subunit：Component of the mitochondrial contact site and cristae organizing system (MICOS) complex, composed of at least MICOS10/MIC10, CHCHD3/MIC19, CHCHD6/MIC25, APOOL/MIC27, IMMT/MIC60, APOO/MIC23/MIC26 and MICOS13/MIC13 (PubMed:25764979, PubMed:25781180, PubMed:32567732).

Research Field

Signal Transduction

Synonyms

HMP; P87; P89; PIG4; Mic60; PIG52; MINOS2; P87/89

Documentation

User Guide for Antibodies (1077 KB)